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27,306 recruiting studies available now

Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial

Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing …

Ulcerative Colitis

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT05987852

Observational

Tear Fluid Collection in Patients Before and After Corneal Incision or Trauma.

Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.

Ocular Trauma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

InnSight Technology, Inc.NCT07887425

Phase 1

Merging Strategy That Uses Gut Microbiome Profiling and Targeted Modulation to Improve CAR-T Cell Therapy Outcomes, Predict Responses, and Reduce Toxicity

Chimeric Antigen Receptor T-Cell (CAR-T) therapy has transformed the management of large B-cell lymphoma, and multiple myeloma by achieving remarkable response…

Lymphoma, B-CellMultiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ChicagoNCT07871747

Phase 3

A Phase 3 Randomized 3-arm Trial (Double-blind Debio 4126, Placebo Control, and Open-label Debio 4126), to Assess the Efficacy and Safety of Debio 4126, a 12-week Octreotide Formulation, in Patients With Acromegaly Previously Treated With Somatostatin Analogs

The primary purpose of this study is to assess the effect of Debio 4126 in the maintenance of the levels of insulin-like growth factor 1 (IGF-1) ≤1x upper limi…

Acromegaly

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Debiopharm International SANCT06930625

Phase 2

A Pilot, Randomized, Open-Label Trial of the Effects of Switch to Doravirine/Islatravir vs. Continued Antiretroviral Therapy on Biomarkers of Aging Among Virologically Suppressed People With HIV

The purpose of this study is to quantify biologic aging (using validated epigenetic clocks) as downstream indicators of Long Interspersed Nuclear Element-1 (LI…

Epigenetic Aging

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT07871552

Phase 1

A PHASE 1/2A STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTI-TUMOR ACTIVITY OF PF-07220060 AS A SINGLE AGENT AND AS PART OF COMBINATION THERAPY IN PARTICIPANTS WITH ADVANCED SOLID TUMORS

This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 adm…

LiposarcomaProstate CancerAdvanced Breast Cancer+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

PfizerNCT04557449

Phase 1

Causal Mechanisms of Odor-Guided Behavior in Humans

Background: Little is known about how different regions of the brain responsible for the human sense of smell guide behaviors. In this study, researchers use …

Normal Physiology

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute on Drug Abuse (NIDA)NCT07099092

Observational

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

The primary purpose of this research study is to determine if forces within carbon fiber custom dynamic orthoses (CDOs) can be reliability assessed using Loadp…

HealthyAnkle Foot Orthosis (AFO)Peripheral Neuropathy

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT06127264

Observational

Screen Smart: Using Digital Health to Improve HIV Screening and Prevention for Adolescents in the Emergency Department

The goal of this interrupted time series quasi-experimental design study is to implement universal opt- out HIV testing and linkage to HIV preventive care in 1…

HIV Infections

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT06003192

Study of Oral Food Challenge Biomarkers (CoFAR-15)

This is a multi-center, mechanistic study. It is designed to learn more about signs in the body, called biomarkers, that might show if someone will have a reac…

Allergy

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT07279467

Phase 2

Mitigating Diabetic Ketoacidosis in People With T1D and Chronic Kidney Disease on an SGLT1&2 Inhibitor: Ketosis Risk Factor Determination and Incorporation Into an Enhanced Glucose Ketone Report

The goal of this clinical trial is to develop and evaluate a novel diabetes ketoacidosis risk mitigation strategy to support the safe use of sodium-glucose cot…

Type 1 Diabetes MellitusChronic Kidney Disease (CKD) With Diabetes Mellitus (DM)Chronic Kidney Disease+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

HealthPartners InstituteNCT07325201

Phase 1

ENDEAVOR: A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Infants and Children With SCN1A-Positive Dravet Syndrome

ENDEAVOR is a Phase 1/2, 2-part, multicenter study to evaluate the safety and efficacy of ETX101 in participants with SCN1A-positive Dravet syndrome aged ≥6 to…

Dravet Syndrome

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Encoded TherapeuticsNCT05419492