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A Phase 1, Open-Label, Dose-Escalation Study to Determine an Appropriate Starting Dose of Sacituzumab Govitecan in Subjects With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

The goals of this clinical study are to learn more about the safety and dosing of the study drug, sacituzumab govitecan-hziy, in participants with solid tumors…

Advanced or Metastatic Solid TumorLiver Failure

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Gilead SciencesNCT04617522

Phase 1

A Phase 1/2 Study of OR502 Alone and in Combination With Other Anti-cancer Agents in Subjects With Advanced Malignancies

This is an open-label, multicenter, first-in-human dose-escalation and expansion Phase 1-2 study designed to determine the safety, tolerability, pharmacokineti…

CancerTumor, SolidMalignant Neoplasm+4 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

OncoResponse, Inc.NCT06090266

Observational

A Reinforced Mindfulness-Based Intervention to Reduce Problematic Drinking Among Hispanic Emerging Adults: Feasibility and Acceptability

This study is a trial to evaluate a mindfulness program designed for Hispanic young adults. Participants will be randomly assigned to one of two groups: (1) an…

MBSRYoung AdultsHeavy Episodic Drinking

Estimated

~$10 – $750

Actual pay is set by the research site.

Florida International UniversityNCT07192094

Phase 1

A Phase 1, First in Human, Dose-Escalation Study of TORL-1-23 in Participants With Advanced Cancer

This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-1-23 in patients with advanced cancer

Advanced Solid TumorOvarian CancerEndometrial Cancer+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

TORL Biotherapeutics, LLCNCT05103683

Phase 1

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

This phase Ib trial tests the safety, side effects, and best dose of tumor treating fields therapy in combination with either cabozantinib or nab-paclitaxel an…

Advanced Breast CarcinomaAdvanced Endometrial CarcinomaAdvanced Fallopian Tube Carcinoma+71 more

Observational

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

The purpose of this study is to examine the feasibility of adding pre-rehabilitation pelvic health physical therapy to standard of care radiation therapy treat…

DyspareuniaPelvic PainSexual Dysfunction+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT06059586

Phase 2

A Phase II Randomized Open-Label Trial of Levetiracetam for Prevention of Seizures in Patients With Brain Metastases in Primary Motor Cortex

This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-sei…

SeizuresPrimary Motor CortexBrain Metastases From Non-small Cell Lung Cancer (NSCLC)+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Ayal A. Aizer, MDNCT07130786

Observational

A Feasibility Study of the Ability of the Neural Prosthetic System 2 to Provide Direct Closed Loop Cortical Control of Extracorporeal Devices Through the Use of Intracortical Microstimulation in Patients With Quadriplegia

This research study is being conducted to develop a brain controlled medical device, called a brain-machine interface. The device will provide people with a sp…

Quadriplegia

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Richard A. Andersen, PhDNCT01964261

Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines. DPPMs can cause dysfu…

AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more

Natural History Study of Patients With Excess Androgen

This study will evaluate and gather information in patients with genetic causes of too much androgen (male-like hormone) in order to better understand the effe…

Congenital Adrenal Hyperplasia (CAH)Familial Male-Limited Precocious Puberty (FMPP)

Estimated

~$10 – $675

Actual pay is set by the research site.

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT00250159

Observational

Instillation in Neurogenic Bladders to Decrease Unplanned Healthcare Encounters

The goal of this clinical trial is to evaluate the feasibility and tolerability of 0.05% Chlorhexidine Gluconate (CGH) bladder instillations in an outpatient s…

Neurogenic BladderUrinary Retention

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT06163469

Phase 3

A Double-blind, Randomized, Placebo-controlled, Parallel-controlled, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of a Botanical Total Coumarin Cream (TC Cream) in Treating Patients With Psoriasis Vulgaris

The goal of this clinical trial is to learn if a botanical Total Coumarin topical cream (TC Cream) works to treat psoriasis in adults. It will also learn about…

Psoriasis VulgarisTopical AdministrationPhase III

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Psoriasis Research Institute of GuangzhouNCT07426120