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3,232 recruiting studies matching your filters

Phase 2 Study of Futibatinib 20 mg and 16 mg in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusions or Rearrangements

This is an open-label, multinational, randomized Phase 2 study confirming the clinical benefit of 20 mg futibatinib and evaluating the safety and efficacy of 1…

Advanced CholangiocarcinomaFGFR2 FusionsGene Rearrangement

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Taiho Oncology, Inc.NCT05727176

Addressing Root Causes for Gun Violence Prevention (ARC-GVP) Outcomes Study

The goal of this study is to help build the evidence base for a locally-relevant youth firearm violence prevention program in Washington D.C., a city experienc…

ViolenceAdolescentFirearm Injury+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MichiganNCT05887973

Observational

Toward Healthy Living: Virtual Reality-Infused Treadmill Training on Aging-Related Outcomes

Age-associated motor and cognitive deficits increase the risk of falls, a major cause of morbidity and mortality. Emerging evidence suggests that inflammatory …

Adult ALL

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas at ArlingtonNCT06727942

Phase 1

First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFβ Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-Driven Advanced Solid Tumors

The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical data, this…

Head and Neck Squamous Cell CarcinomaSquamous Cell Carcinoma of Anal CanalColorectal Cancer+8 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Bicara Therapeutics

Phase 1

A Phase 1b/2a Study to Assess the Safety, Pharmacokinetics, and Preliminary Efficacy of TU2218, an Oral TGFβR Serine/Threonine Kinase Inhibitor, Administered in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

This study consists of phase 1b and 2a to evaluate safety, Pharmacokinetics, and efficacy of TU2218 in combination with Pembrolizumab in patients with advanced…

Solid TumorBiliary Tract CancerHead and Neck Squamous Cell Carcinoma+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

TiumBio Co., Ltd.NCT05784688

Phase 2

Imaging of T-cell Activation With [18F]F-araG in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Undergoing PD-1/PD-L1 Directed Therapy

This pilot study uses \[18F\]F AraG PET imaging to evaluate the immunological response to checkpoint inhibitor therapy (CkIT) in patients with advanced NSCLC t…

Advanced Non Small Cell Lung Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

CellSight Technologies, Inc.NCT06107374

Observational

Exploring the Interactive Effects of Sodium and Potassium Intake on Vascular Health in Older Adults

The goal of this clinical trial is to determine if a high potassium intake can counteract the harmful effects of excess sodium on endothelial function in older…

Healthy Older Adults

Estimated

~$10 – $750

Actual pay is set by the research site.

Florida State UniversityNCT07649005

An Exosomal miRNA Based Predictive Model for Personalized Neoadjuvant Chemotherapy Selection in Pancreatic Ductal Adenocarcinoma

This study aims to develop and validate a predictive microRNA (miRNA) panel to assess the response to neoadjuvant chemotherapy (NACT) in patients with resectab…

Pancreatic Ductal Adenocarcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

City of Hope Medical CenterNCT07226154

Investigation of Augmented Reality/Mixed Reality Viewer for Surgical Planning in Cranial Surgery

This study is a prospective observational study designed to evaluate the effectiveness of Brainlab's Mixed Reality Viewer in enhancing the accuracy and efficie…

NeurosurgerySurgical PlanningBrain Tumor Adult+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Brainlab AGNCT07468370

Observational

Using Autologous Epidermal Skin Micrografts to Improve Healing In Radiation Wounds: A Pilot Study

Patients undergoing radiation for the treatment of malignancies may suffer from side effects to the skin in the form of radiation dermatitis. This can lead to …

Radiation Dermatitis

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT04560803

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix - a Rare Tumor

This study aims to provide a comprehensive report on clinicopathologic features, immunohistochemical/biomarker testing and molecular profile of cervical clear …

Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT05046080

Phase 1

Open-Label, Single-Arm, Phase 1b Clinical Trial of NAI Plus Pembrolizumab With Short Course of Enfortumab Vedotin in Treatment-Naïve Participants With Metastatic Urothelial Carcinoma

This phase Ib trial will investigate the effect of N-803 in combination with pembrolizumab and enfortumab vedotin in treating participants with urothelial canc…

Metastatic Urothelial CarcinomaUrothelial CarcinomaLocally Advanced Urothelial Carcinoma+2 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

ImmunityBio, Inc.NCT07217496