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AN INTERVENTIONAL PHASE 1B/2, OPEN-LABEL STUDY TO INVESTIGATE THE SAFETY, ANTITUMOR ACTIVITY, AND PHARMACOKINETICS OF PF 08634404 MONOTHERAPY OR IN COMBINATION WITH ENFORTUMAB VEDOTIN IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER

This study is being done to learn more about a new medicine called PF-08634404. It is for adults with a type of bladder cancer called locally advanced or metas…

Urothelial CancerAdvanced/Metastatic Urothelial CancerUrothelial Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

PfizerNCT07421700

Observational

Urine Resazurin Reduction Ratio and Phenotypic Antibiotic Susceptibility Testing: A Rapid Diagnostic Tool for Urinary Tract Infection and Lower Urinary Tract Dysfunction Using a Catheter

Patients who seek care through MedStar National Rehab Hospital's clinic believing they have a UTI will be enrolled in this trial. They will be pre-screened aft…

Neurogenic Bladder DisorderLower Urinary Tract DisorderUrinary Tract Infection (Diagnosis)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Medstar Health Research InstituteNCT07784829

Phase 1

A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG462 as a Single Agent and in Combination in Patients With MTAP-deleted Advanced or Metastatic Solid Tumors

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-labe…

Locally Advanced Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Tango Therapeutics, Inc.NCT05732831

Phase 2

A Phase 2b, Open Label, Single-Arm, Multi-Center, Multiple Dose, 14-Day Study to Evaluate the Safety, Efficacy, and Frequency of Intravesical Administration of VNX001 in Acute Treatment of Subjects With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Who Have an Episode of Acute Bladder Pain of Moderate to Severe Intensity

This is an open-label study that will enroll participants with Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS). The study will assess PRN (as needed) d…

Interstitial CystitisBladder Pain Syndrome

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Vaneltix Pharma, Inc.NCT06394830

Observational

A Randomized Controlled Trial of a Walking Meditation Intervention (iWalk) to Enhance Resilience in Adults

This study is a randomized controlled trial of the walking meditation intervention (iWalk) program, a multi-component intervention integrating walking meditati…

Neurodegenerative DiseaseEEGMindfulness+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Illinois at Urbana-ChampaignNCT07285954

Observational

Psychological Assessment of Scoliosis Patients Undergoing Surgical Management (PASS)

Working in partnership with Montefiore-Einstein's Department of Translational Psychiatry, the investigators have designed a prospective randomized clinical tri…

Adolescent Idiopathic Scoliosis (AIS)Mental Health

Estimated

~$10 – $750

Actual pay is set by the research site.

Montefiore Medical CenterNCT05774002

Phase 1

A Maximal Use Trial of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

The purpose of this study is to evaluate the maximal use of ruxolitinib cream in adult and adolescent participants with hidradenitis suppurativa.

Hidradenitis Suppurativa

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Incyte CorporationNCT07049575

The T-cell Lymphoma Master Repository (TCLMR): A Prospective Databank of Patients With T-cell Lymphoma With Clinical Annotation and Matched Tumor Specimens

The purpose of this registry study is to create a database-a collection of information-for better understanding T-cell lymphoma. Researchers will use the infor…

T-cell LymphomaNK-Cell LymphomaT-cell Prolymphocytic Leukemia+28 more

Observational

Cognitive Behavioral Therapy Via Telehealth + Amitriptyline Compared to Cognitive Behavioral Therapy Via Telehealth: Pediatric Migraine Prevention (Responding With Evidence and Access for Childhood Headaches)

This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care p…

HeadacheHeadache DisordersHeadache, Migraine+5 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT05889624

Observational

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in pre…

DepressionPosttraumatic Stress DisorderPregnancy Related+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston University Charles River CampusNCT05624931

Observational

Social Media Use Study

The investigators will be randomizing 300 college student participants with high levels of social media use into either a 1) control condition (no intervention…

Social Media AddictionAnxietyDepression Disorder+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Johns Hopkins Bloomberg School of Public HealthNCT07097545

Phase 1

Phase I Clinical Trial of Anti-CD19/20/22 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Lymphoid Malignancies (Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia, B-Prolymphocytic Leukemia)

This phase I trial tests the safety, side effects and best infusion dose of genetically engineered cells called anti-CD19/CD20/CD22 chimeric antigen receptor (…

Recurrent Acute Lymphoblastic LeukemiaRecurrent B Acute Lymphoblastic LeukemiaRecurrent B-Cell Prolymphocytic Leukemia+15 more

Estimated