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3,226 recruiting studies matching your filters

A Phase 1, Open-label, Dose Escalation and Dose Expansion Study for LNCB74, a B7-H4 Targeted Antibody Drug Conjugate, as Monotherapy in Participants With Advanced Solid Tumors

This is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and …

Ovarian CancerBreast CancerEndometrial Cancer+2 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

LigaChem Biosciences, Inc.NCT06774963

Observational

Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System

Background: Researchers are testing version of a system known as a magnetic resonance imagining (MRI) scanner that uses strong magnetic fields, radio waves an…

CAD

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT03331380

Observational

Group Singing or Solo Singing to Improve Vascular Health in Older Adults With Coronary Artery Disease: A Feasibility Study

Unlike traditional physical exercise, the impact of singing on cardiovascular health has not been extensively studied. Endothelial dysfunction predicts cardiov…

ElderlyCoronary Arterial Disease (CAD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Medical College of WisconsinNCT07881692

Pancreatic Cancer Early Detection Consortium

The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancr…

Pancreas CancerPancreas CystPancreatic Ductal Adenocarcinoma+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Arbor Research Collaborative for HealthNCT04970056

Phase 1

A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Background: Small cell lung cancer (SCLC) is the deadliest form of lung cancer. Extrapulmonary neuroendocrine cancer (EPNEC) is a similar type of cancer that …

Recurrent Small Cell Lung CancerExtensive-Stage Small Cell Lung CancerSmall Cell Lung Cancer+6 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)

Phase 1

A PHASE 1, OPEN-LABEL STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND ANTITUMOR ACTIVITY OF PF-08098488 IN ADULT PARTICIPANTS WITH ADVANCED SOLID TUMORS.

The purpose of this clinical study is to learn about the safety and effects of the study medicine (called PF-08098488) in people with advanced solid tumors (ca…

Pancreatic Ductal AdenocarcinomaEsophageal CancerCarcinoma, Non-Small-Cell Lung (NSCLC)+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

PfizerNCT07903415

Observational

QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428) is Frontier AI/AGI Public Health Trials Sandbox Framework That Provides Free Public Health Services to Registered and Sponsored Visitors/Occupants for RDT&E Under 28 U.S.C. 1498 (Classified as a PPA, OTA Under 10 U.S. Code 4001, 4022), Serving as a Global Intranet of Humans Resident Patients Among Multiple Enclave Communicates ("AI Microcities" or "Smart Health Cities") Living and Learning With SI Robotics for Non-medicinal Treatment.

BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the …

Asperger's DisorderAsperger DisorderAutism Disorder+41 more

Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer

This study investigates the effects of brain radiotherapy on cognitive function by evaluating plasma biomarkers and apolipoprotein E (APOE) genotype in patient…

Brain Tumor AdultBrain Metastases From Solid TumorsBrain Tumor, Primary+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT07226466

Phase 2

A Multicenter, Randomized, Double-blind, Phase 2/3 Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab for First-Line Treatment of PD-L1-positive, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Ficerafusp alfa is directed against two targets, Epidermal Growth Factor Receptor (EGFR) and Transforming Growth Factor beta (TGF-β). This study intends to ev…

Metastatic Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell Carcinoma

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Bicara TherapeuticsNCT06788990

Phase 3

A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine Versus Selumetinib (NSC# 748727) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) Not Associated With BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)

This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with n…

Low Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04166409

Phase 1

A Pilot Study of Zimberelimab and Quemliclustat Combination With Chemotherapy in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

This phase I/II study tests how well zimberelimab and quemliclustat work in combination with chemotherapy (mFOLFIRINOX) in treating patients pancreatic adenoca…

Borderline Resectable Pancreatic AdenocarcinomaLocally Advanced Pancreatic Ductal Adenocarcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Jonsson Comprehensive Cancer CenterNCT05688215

Phase 2

A Phase 2, Randomized, Parallel-Group, Double-Blind, Study to Evaluate the Safety and Efficacy of ALKS 7290 Compared to Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder

The purpose of this study is to measure safety and the improvement in symptoms in subjects with ADHD when taking ALKS 7290 tablets compared with placebo tablet…

Attention Deficit Disorder With Hyperactivity (ADHD)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Alkermes, Inc.NCT07755410