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3,219 recruiting studies matching your filters

Use of 18F-Fluciclovine PET for Discerning Tumor From Treatment Change in Patients With Brain Metastases Undergoing Immunotherapy

The goal of this clinical trial is to use new imaging methods to help in finding out whether the imaging shows that there is a tumor in people with a brain met…

Brain MetastasisRadiation TherapyImmunotherapy, Active

Estimated

~$50 – $1,500

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT06159335

Phase 4

Intraoperative Methadone for Postoperative Pain Management in a Head and Neck Oncology Population - A Prospective, Randomized Controlled Trial

This phase IV trial compares how well methadone plus standard fentanyl given during surgery (intraoperative) works compared to intraoperative standard fentanyl…

Head and Neck CarcinomaHypopharyngeal CarcinomaLaryngeal Carcinoma+2 more

Estimated

~$25 – $1,500

Actual pay is set by the research site.

OHSU Knight Cancer InstituteNCT07857655

Observational

Virtual Reality Travel (VRT) as a Loneliness Intervention for Older Adults: A Pilot Randomized Controlled Trial

This study aims to investigate whether and how virtual reality travel (VRT) can reduce loneliness among older adults. It will utilize a mixed-methods research …

LonelinessOlder Adults (65 Years and Older)Virtual Reality+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT07644416

Phase 3

RASolve 301: Phase 3 Multicenter, Open Label, Randomized Study of RMC-6236 Versus Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic RAS[MUT] NSCLC

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to docetaxel.

NSCLC (Non-small Cell Lung Cancer)Non-Small Cell Lung CancerNSCLC+2 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Revolution Medicines, Inc.NCT06881784

Phase 2

A Phase 2 Window of Opportunity Trial of Neoadjuvant Agonistic Anti-CD40 Antibody CDX-1140 and Cemiplimab (REGN2810) in AJCC Stage III-IV Head and Neck Cancer Patients Prior to Surgery

This phase II trial compares the effectiveness of cemiplimab with CDX-1140 to cemiplimab without CDX-1140 prior to surgery in treating patients with stage III-…

Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell Carcinoma+19 more

Estimated

Observational

Influenza Immunization in Adults Over Age 75

The immune system is the part of the body that protects against infection. The immune system often doesn't work as effectively as people get older. This resear…

InfluenzaImmunizationOlder Adults+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Johns Hopkins UniversityNCT02200276

Observational

Using Bitter Taste Receptor Blockers to Improve the Palatability of Pediatric Medicines: Trained Human Sensory Panels

Many people, particularly small children, must take drugs in liquid form because they cannot swallow pills or capsules. The bad taste of some liquid drugs can …

Healthy Adults

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Monell Chemical Senses CenterNCT06929455

Phase 1

Phase 1 Dose-escalation Trial of OMTX705, an Anti-fibroblast Activation Protein Antibody-drug Conjugate, as Single Agent and in Combination With Anti-PD-1 in Patients With Advanced Solid Tumors

Open-label, two parallel arm, multicenter, Phase 1 dose-escalation study to evaluate the safety and tolerability of OMTX705, both as monotherapy or in combinat…

Advanced Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Oncomatryx Biopharma S.L.NCT05547321

Phase 1

SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency

The overall objective of this study is to determine the safety and efficacy of AAV2-hAADC delivered to the substantia nigra pars compacta (SNc) and ventral teg…

AADC Deficiency

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Krzysztof BankiewiczNCT02852213

Measurement of Brain NAD Levels in Alzheimer's Patients and Control Subjects by 1H-MRS

The goal of this observational study is to learn about the levels of nicotinamide adenine dinucleotide (NAD) in the brains of people with Alzheimer's disease. …

Alzheimer Disease (AD)

Estimated

~$10 – $750

Actual pay is set by the research site.

Florida Atlantic UniversityNCT07127510

Phase 3

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Adaptive Study of iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma

This Phase 3 clinical trial is evaluating whether adding iSCIB1+, an investigational DNA-based cancer vaccine, to standard immunotherapy with nivolumab and ipi…

Melanoma (Skin Cancer)Advanced MelanomaMetastatic Melanoma+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Scancell LtdNCT07815574

Phase 1

A Phase 1 Study of MOMA-341 as Monotherapy or Combination Therapy in Participants With Advanced or Metastatic Solid Tumors

This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), phar…

Advanced Solid TumorMetastatic Solid TumorEndometrial Cancer+4 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

MOMA TherapeuticsNCT06974110