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1,574 recruiting studies matching your filters

Perinatal Accelerated iTBS Neuromodulation Therapy

We are studying a treatment for depression called accelerated Transcranial Magnetic Stimulation (TMS) among pregnant and postpartum individuals. TMS is a focal…

Perinatal DepressionPost Partum DepressionMajor Depressive Disorder

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT06968390

Observational

The Effects of Transcutaneous Vagus Nerve Stimulation (tVNS) on Acute Pain Perception and Brain Activity in Healthy Adults

The goal of this clinical trial is to learn whether stimulating a nerve in the neck changes how much pain people feel. It also looks at whether this stimulatio…

Acute PainPain PerceptionHealthy Adult Participants

Estimated

~$10 – $7,500

David A. PurgerNCT07827690

Observational

Improving the Collaborative Health of Adults With Chronic Conditions & Carepartner Dyads Through Interventions Addressing Social and Health Self-Management Needs.

This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of adults with pre-existing chronic health conditions and th…

Cardiovascular DiseasesChronic Kidney DiseasesDiabetes Mellitus, Type 2+4 more

Estimated

~$10 – $6,250

University of South CarolinaNCT05370014

Observational

A Pilot Single-center Randomized Controlled Trial of Software Guided Point-of-care

The purpose of the study is to implement point of care ultrasound (POCUS) to generate preliminary, or pilot, data to support a full future POCUS study across m…

Heart Failure With Reduced Ejection Fraction

Estimated

~$10 – $7,500

Corewell Health WestNCT07828834

Vonoprazan Pregnancy Registry: An Observational Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

The main objective of the study is to compare the maternal, fetal, and infant outcomes of pregnant women who are exposed to vonoprazan during pregnancy with ou…

Erosive EsophagitisHeartburnSymptomatic Non-erosive Gastroesophageal Reflux Disease+1 more

Estimated

~$10 – $1,050

Phathom Pharmaceuticals, Inc.NCT06660342

Phase 2

An Extension Study to Evaluate the Long-term Safety and Efficacy of Afimkibart (RO7790121) in Patients With Rheumatoid Arthritis Who Participated in Previous Afimkibart Clinical Trials

The study will evaluate the long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with moderate to severe Rheumatoid Arthritis …

Rheumatoid Arthritis

Estimated

~$10 – $7,500

Hoffmann-La RocheNCT07620392

Phase 1

A Multicenter Open-label, Prospective Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Primary purpose of the study is to assess the concentration of bimekizumab in mature human breast milk.

Moderate to Severe Plaque PsoriasisPsoriatic ArthritisAxial Spondyloarthritis+1 more

Estimated

~$10 – $8,750

UCB Biopharma SRLNCT06888193

Phase 1

A Phase 1, Single-Center, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability and Pharmacokinetics in Plasma, Urine and CSF of Single and Multiple Ascending Doses of ALZ-507 in Healthy Participants

Researchers are testing an investigational medicine called ALZ-507 in healthy adults between 50 and 75 years of age. The purpose of this study is to learn: A…

Healthy Participants Study

Estimated

~$10 – $8,750

Alzheon Inc.NCT07824271

Phase 1

An Open-label, Single-sequence Multiple Cohort Study to Assess the Effect of Multiple Doses of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on the Pharmacokinetics of Single Doses of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity

This study will measure the effects of multiple doses of AZD6234, AZD9550 and a combination of AZD9550 and AZD6234 given as injection(s) on pharmacokinetics (P…

Healthy Participants

Estimated

~$10 – $7,500

AstraZenecaNCT07013643

Hepatic Perfusion and Liver Health as Assessed by Dual Cholate Clearance Assay in Fontan-associated Liver Disease (FALD)

The goal of this study is to use the HepQuant dual cholate clearance assay, which has been shown to measure liver function in people with known chronic liver c…

FontanRight Heart Failure

Estimated

~$10 – $1,050

HepQuant, LLCNCT07009132

Phase 3

A Multi-Center, Randomized, Double-Blind, Placebo- and Active-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Zasocitinib (TAK-279) in Subjects With Active Psoriatic Arthritis Who Are Naïve to Biologic Disease-Modifying Antirheumatic Drugs (LATITUDE-PsA-3001)

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects the joints and skin in people who have psoriasis (PsO). The main aim of the study is …

Phase 3b/4, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Trial to Evaluate the Efficacy and Safety of Daily Subcutaneous Injections of Elamipretide in Patients With Genetically Confirmed Barth Syndrome

Phase 3b/4, randomized, double-blind, parallel-group, placebo-controlled clinical trial to evaluate the efficacy, safety, and pharmacokinetics of a once daily …

Barth Syndrome

Estimated

~$10 – $8,750

Stealth BioTherapeutics Inc.NCT07531251