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1,574 recruiting studies matching your filters

Endocardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment: A 26-Week (With 26 Week Extension) Phase 2b Randomized, Multi-Center, Double-Blind, Sham Controlled Study to Evaluate Efficacy and Safety

This is a two-part study, comprised of an initial open-label run-in phase (Part 1) in a subset of 3 subjects to provide first data regarding safety, and feasib…

Refractory AnginaCoronary Artery Disease

Estimated

~$10 – $8,750

XyloCor Therapeutics, Inc.NCT07048808

Observational

Personalizing Post Surgical Thromboprophylaxis for Patients With Peripheral Artery Disease

The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peri…

Peripheral Arterial Disease (PAD)AmputationThrombosis+4 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07613840

Phase 1

Phase 1b/2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study Assessing the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of HS235 Added to Background Treatment in Adults With PAH

Phase 1b/2 Study of HS235 Assessing the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of the Activin Signaling Inhibitor HS235 Added to Background T…

Pulmonary Arterial Hypertension

Estimated

~$10 – $8,750

35Pharma IncNCT07143448

Evaluating Three-Year Outcomes For Total Versus Reverse Shoulder Arthroplasty

The purpose of this multicenter observational cohort study is to evaluate three-year outcomes in adults who underwent anatomic or reverse total shoulder arthro…

Arthroplasty, Replacement, ShoulderArthritis ShoulderRotator Cuff Arthropathy

Estimated

~$10 – $1,125

Vani SabesanNCT07815535

Phase 1

A Phase 1, Randomized, Double Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of SAB01 in Healthy Participants

SAB01 is an investigational bispecific monoclonal antibody targeting mast cells. This first-in-human Phase 1 clinical trial evaluates the safety, pharmacokinet…

Healthy Adult Participants

Estimated

~$10 – $7,500

Santa Ana BioNCT07815561

A Real-World Post-Market Clinical Follow-Up Study to Evaluate the Safety and Performance of Getinge's Beating Heart Product Family in Patients Undergoing Beating Heart Coronary Artery Bypass Graft Surgery

This observational study aims to collect data on the performance and safety of Getinge's Beating Heart products used during open-heart coronary artery bypass g…

Off Pump Coronary Artery Bypass Surgery

Estimated

~$10 – $1,125

Maquet CardiovascularNCT07286890

Phase 3

A Phase 3, Parallel-group, Randomized, Double-blind, 4-arm, Placebo-controlled, Multicenter Study With Risankizumab as Active Reference Arm, to Investigate the Efficacy and Safety of Subcutaneous Sonelokimab in Male and Female Participants Aged 18 Years and Over With Active Psoriatic Arthritis and Previous Inadequate Response or Intolerance to Tumor Necrosis Factor-α Inhibitors

This is a study to confirm the clinical efficacy and safety of sonelokimab compared with placebo in the treatment of adults with active psoriatic arthritis who…

Arthritis, Psoriatic

Estimated

~$10 – $8,750

MoonLake Immunotherapeutics AGNCT06641089

Observational

Effects of Maternal Stress on Human Milk Composition and Subsequent Infant Outcomes

The overarching purpose of this study is to determine if a modified 8-week mindfulness-based intervention (with a focus on self-compassion; MBSC) or 8 weeks of…

Postpartum DepressionPreterm Labor

Estimated

~$10 – $6,250

University of IdahoNCT04821544

Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability

Heart failure due to coronary artery disease represents a significant cause of mortality. The detection of patients eligible for bypass surgery is a pivotal co…

Coronary Artery DiseaseIschemic Heart Disease (IHD)Myocardial Viability

Estimated

~$10 – $750

University of Texas Southwestern Medical CenterNCT06047028

Post-Market Clinical Follow-up Registry to Evaluate the Safety and Performance of the Intervascular Vascular Grafts and Patches in Patients Undergoing Bypass, Replacement, or Repair of Aortic, Peripheral, or Carotid Arteries

The purpose of this registry is to evaluate the long-term safety and performance of Intervascular Vascular Grafts and Patches (Intergard Standard, Hemashield, …

Carotid Artery DiseasesAortic DiseasesPeripheral Arterial Diseases

Estimated

~$10 – $1,125

IntervascularNCT07322913

Post-Market Clinical Follow-up Registry to Evaluate the Safety and Performance of the Atrium Advanta VXT and Flixene Vascular Grafts in Patients Undergoing Surgical Repair or Replacement of Peripheral Arteries

The purpose of the registry is to evaluate the long-term safety and performance of Advanta VXT and Flixene vascular grafts for repair or replacement of periphe…

Peripheral Arterial Disease

Estimated

~$10 – $1,050

Atrium Medical CorporationNCT07161583

Phase 1

Phase 1/2 Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM

Background: Warts, hypogammaglobulinemia, infections and myelokathexis syndrome (WHIMs) is a rare disorder that affects the immune system. People with WHIMs c…

WHIMWartsHypogammaglobulinemia+2 more

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT07775313