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1,574 recruiting studies matching your filters

Capitalizing on AI to CapTure Undiagnosed Structural Heart Disease

Doctors are testing a new tool called EchoNext to see if it can help find heart problems earlier. EchoNext looks at the heart's electrical test, called an ECG,…

Structural Heart AbnormalityValve Heart DiseaseHeart Diseases+1 more

Estimated

~$10 – $7,500

Pierre EliasNCT07843004

Phase 1

A Phase 1, First-in-Human, Single Ascending Dose, Open-label, Non-randomized Study Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of ABBV-519 in Subjects With Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA)

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by B cell hyperactivity. Rheumatoid Arthritis (RA) is a chronic inf…

Systemic Lupus ErythematosusRheumatoid Arthritis

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

This study is an open-label, randomized, multicenter trial that incorporates a multi-arm design comparing each of 3 non-TNFi (Tumor Necrosis Factor inhibitor) …

Polyarticular Course Juvenile Idiopathic Arthritis (JIA)

Estimated

~$10 – $6,250

Duke UniversityNCT06654882

Phase 2

A Randomized, Double-blind, Placebo-controlled, Multicenter Phase 2a/b Study Assessing the Efficacy, Safety and Tolerability of DDY391 in Participants With Active Moderate to Severe Psoriatic Arthritis

The purpose of this Phase 2a/b study is: 1. to evaluate the efficacy, safety and tolerability of DDY391 in participants with psoriatic arthritis (PsA). 2. to …

Moderate to Severe Psoriatic Arthritis

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07801495

Phase 1

A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants

The main purpose of this study is to determine the effect of vimseltinib on pharmacokinetics of P-glycoprotein (P-gp) substrate (dabigatran) in healthy male pa…

Healthy Male Participants

Estimated

~$10 – $8,750

Deciphera Pharmaceuticals, LLCNCT07744802

Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory Conditions

Background: Inflammatory conditions can cause symptoms like fevers, arthritis, and rash. Systemic juvenile idiopathic arthritis (sJIA) is one of these conditi…

Still's Disease, Adult-OnsetSystemic InflammationArthritis+1 more

Estimated

~$10 – $675

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT03510442

A Longitudinal Study of Orbital and Cranial Vessel Wall MRI in Giant Cell Arteritis by the Vascular MRI Evaluation in Giant Cell Arteritis (VEGA) Collaborative

The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to t…

Giant Cell Arteritis

Estimated

~$10 – $750

University of PennsylvaniaNCT05865054

Phase 3

CNTO1959ISD3001: A Phase 3, Multicenter, Open-label, Basket, Long-term Extension Study to Evaluate the Safety of Guselkumab in Pediatric Participants With Crohn's Disease, Ulcerative Colitis, or Juvenile Psoriatic Arthritis

The purpose of this study is to evaluate long-term safety of subcutaneous guselkumab in pediatric participants with moderately to severely active ulcerative co…

Crohns DiseaseColitis, UlcerativeArthritis, Psoriatic+1 more

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT06663332

Long-Term CLinical Evaluation of Aspiration ThRombectomy Using the Symphony or ProdIgy Thrombectomy System - CLEAR-IT

The study is designed to evaluate the short-term and long-term clinical performance and safety of the Symphony and Prodigy thrombectomy systems used in endovas…

Arterial ThromboembolismVenous ThromboembolismPulmonary Embolism

Estimated

~$10 – $1,050

Imperative Care, Inc.NCT07350499

Pulse Oximetry Accuracy and Skin Pigmentation in Congenital Heart Disease: A Prospective Observational Study

Recent retrospective studies have demonstrated differences between pulse oximeter values (SpO2) and measured arterial oxygen saturation (SaO2) in patients iden…

HypoxemiaSkin PigmentCongenital Heart Disease

Estimated

~$10 – $750

Icahn School of Medicine at Mount SinaiNCT06575270

Observational

A Single-Center, Randomized, Pilot Study to Assess the Clinical Effectiveness of EXPAREL as an Intra-articular Posteromedial Surgeon Administered (IPSA) Block in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty

Intra-articular Posteromedial Surgeon Administered (IPSA) Block in this study describes a new type of medical procedure where a surgeon provides anesthetic med…

Total Knee Arthroplasty

Estimated

~$10 – $6,250

The Cleveland ClinicNCT06946368

Phase 2

A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of JNJ-88545223 For the Treatment of Participants With Active Psoriatic Arthritis

The purpose of this study is to evaluate how well the study drug JNJ-88545223 works compared with a placebo (an inactive substance) in adults with active psori…

Arthritis, Psoriatic

Estimated

~$10 – $8,750

Janssen Research & Development, LLCNCT07321873