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ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
The aim of this study is to conduct a comparative evaluation of the ROAM OA Single Upright Brace and the Ossur Unloader One Knee Brace in subjects with medial …
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
The purpose of this research is to determine if two proteins in the blood are increased during acute heart failure. These two proteins are produced when the he…
Medtronic Cardiac Surgery Post Market Clinical Follow-up Registry
This registry is being conducted to support ongoing post-market surveillance activities.
Response to Exercise and Nitric Oxide in Peripheral Artery Disease: The RESIST PAD Trial
RESIST PAD is a randomized trial of 200 PAD patients to establish: 1) whether a 12-week exercise intervention significantly increases Δ nitrite at 12-week foll…
Application of a Novel Antimicrobial Wash Versus Hydrogen Peroxide Versus Povidone-iodine to the Dermis and Incidence of Cutibacterium Acnes During Shoulder Arthroplasty: A Randomized Controlled Trial
The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of pos…
The Role of NEUROCUPLE™ as an Alternative to Opioids Following Total Knee Arthroplasty Patients
The goal of this clinical trial is to learn if the NEUROCUPLE device can reduce pain and opioid use after primary unilateral total knee arthroplasty (TKA) in a…
Trapeziectomy and Suture Suspensionplasty for Thumb Carpometacarpal Arthritis - Is In-Clinic Therapy Needed?
The study is a randomized, controlled trial to evaluate the efficacy of formal occupational therapy on outcomes following CMC arthroplasty
A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System
The goal of this study is to demonstrate the safety and performance of the Incompass™ Total Ankle System after surgery over the standard follow-up period. The …
Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure
This study is an investigator-initiated, cluster-randomized implementation trial evaluating a large language model (LLM)-based clinical decision support (CDS) …
Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts (DART-HA)
The DART-HA study is a single-center, open label, trial intended to evaluate the clinical efficacy of standard treatment options for congestive heart failure (…
Low Level Transcutaneous Tragus Stimulation to Reduce Inflammation, Dyspnea and Improve Heart Rate Variability in Acute Decompensated Heart Failure
Acute Decompensated Heart Failure (ADHF) is a major cause of morbidity and mortality. It is associated with increased systemic inflammation. Previous studies h…
Feasibility and Acceptability of Three Component Intervention for the Heart Failure Care for Rural Dwelling Participants
The purpose of this research study is to determine if using remote blood pressure monitoring and video-based consultation is an effective way to help patients …