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Phase 2
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL) - (Optimizing Acute Stress Reaction Interventions With TNX-102 SL - OASIS)
This study will examine the safety and efficacy of TNX-102 SL to reduce ASR symptoms and behavioral changes among patients presenting to the emergency departme…
Acute Stress ReactionAcute Stress DisorderNeurocognitive Function+1 more
University of North Carolina, Chapel HillNCT06636786
Phase 2
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With a Sublingual Formulation of Dexmedetomidine (BXCL501)
This study will examine the safety and efficacy of BXCL501 to reduce ASR symptoms and behavioral changes among patients presenting to the Emergency Department …
Acute Stress ReactionAcute Stress DisorderPost-traumatic Stress Disorder
University of North Carolina, Chapel HillNCT06943404
Observational
Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety: A Randomized Clinical Trial
Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided r…
Anxiety DisordersTraumaGeneralized Anxiety Disorder+7 more
University of Texas at AustinNCT05427708
Observational
Adolescent Injury: Intervening to Prevent Posttraumatic Stress and Substance Use Outcomes
The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with…
PTSDSubstance Use Disorder (SUD)Acute Stress Disorder
Rhode Island HospitalNCT07197476