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1,513 recruiting studies matching your filters

Phase II Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in PD-L1-Negative or Immunotherapy-refractory Esophagogastric Adenocarcinoma

The goal of this study is to learn about of the research study drug, telomelysin (OBP-301), in combination with pembrolizumab in advanced or metastatic gastric…

Esophageal AdenocarcinomaGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma

Estimated

~$10 – $6,250

Weill Medical College of Cornell UniversityNCT06340711

Phase 4

The Role of SNRI's in the Prophylaxis of Depression in the First Year Following Lower Extremity Fragility Fractures in Geriatric Patients

The goal of this pilot study is to learn about the feasibility about prescribing anti-depressants at discharge in patients aged 50 years and older with a lower…

Depression in Old AgeFragility Fracture

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT05851898

Phase 4

CAT BITE Antibiotic Prophylaxis and Durations for the Hand/Forearm (CATBITE): A Prospective, Randomized, Placebo-controlled, Double-blinded, Clinical Trial

Cat bites are puncture wounds that have the potential to seed bacteria deep within the joint capsule, periosteum, and bone. The hand is the most common site of…

Cat BiteHand InjuriesArm Injury+2 more

Estimated

~$10 – $6,250

University of Missouri-ColumbiaNCT05846399

Observational

Exercise as Treatment in Children With Communication Impairments

This clinical trial study has two goals. The first goal is to establish fitness levels, participation in physical activities, and fine/gross motor abilities fo…

Developmental Language Disorder

Estimated

~$10 – $6,250

Marquette UniversityNCT06340893

Phase 3

Phase III Trial of Immunotherapy-Based Combination Therapy With or Without Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma (PROBE Trial)

This phase III trial compares the effect of adding surgery to a standard of care immunotherapy-based drug combination versus a standard of care immunotherapy-b…

Metastatic Clear Cell Renal Cell CarcinomaMetastatic Renal Cell CarcinomaStage IV Renal Cell Cancer AJCC v8

Estimated

~$10 – $7,500

SWOG Cancer Research NetworkNCT04510597

Feasibility and Correlation of Functional Muscle Strength Tests and Objective Frailty Measures With Clinical Frailty Scale in Patients Undergoing Major Surgery

The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at …

FrailtySarcopeniaSarcopenia in Elderly+6 more

Estimated

~$10 – $750

University of North Carolina, Chapel HillNCT06988176

Observational

Randomized Controlled Trial of Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social functio…

Cancer PainVisceral PainGastrointestinal Neoplasms+76 more

Phase 1

A Phase I Study of Venetoclax in Combination With Cytotoxic Chemotherapy, Including Calaspargase Pegol, for Children, Adolescents and Young Adults With High-Risk Hematologic Malignancies

This trial is evaluating the safety and tolerability of venetoclax with chemotherapy in pediatric and young adult patients with hematologic malignancies, inclu…

Myelodysplastic Syndromes, de NovoMyelodysplastic Syndromes, SecondaryMyelodysplastic Syndromes, Previously Treated+8 more

Estimated

~$10 – $7,500

Andrew E. Place, MD

EsophaCap for the Detection of Early Esophageal Carcinoma

This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carc…

Barrett EsophagusEsophageal CancerGastric Cancer

Estimated

~$10 – $750

Johns Hopkins UniversityNCT04214119

Phase 1

A Phase1/2a, Open-Label Study to Evaluate the Safety and Tolerability of RPE Stem Cell-derived RPE (RPESC-RPE) Transplantation as Therapy for Dry Age-related Macular Degeneration (AMD)

The main objective of the study is evaluation of the safety and tolerability of RPESC-RPE-4W as therapy for dry AMD.

Dry Age-related Macular Degeneration

Estimated

~$10 – $8,750

Luxa Biotechnology, LLCNCT04627428

Phase 2

High Cannabidiol (CBD) Standardized Extract for Aromatase Inhibitor-Induced Arthralgia - A Randomized Controlled Double Blind Clinical Trial

This phase II trial tests the effectiveness of cannabidiol (CBD) plant extract (BRC-001) in improving joint stiffness and pain (arthralgia) in women with breas…

Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8+5 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT06538389

Phase 2

Phase 2 Study of Bright White Light During Treatment With ADT Combination Therapy in Men With Advanced Prostate Cancer to PreServe PHysIcal and MeNtal HEalth (SHINE)

This phase II trial tests how well bright white light (BWL) therapy works in reducing cancer-related fatigue and depression in patients with prostate cancer th…

Advanced Prostate CarcinomaMetastatic Prostate CarcinomaProstate Carcinoma+2 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT05869682