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Innovative Cognitive-Motor Training for Prevention of AD/ADRD
Alzheimer's disease and related dementias (AD/ADRD) greatly affect memory and daily activities in older adults. Mild Cognitive Impairment (MCI) is an early sta…
An Examination of Psilocybin Effects on Biomarkers of Longevity, Healthy Aging, and Purpose in Life
The LONG-LIFE study is a randomized Phase I, dose-ranging trial designed to evaluate whether psilocybin impacts aging-related biomarkers, cognitive function, a…
Targeting Intramuscular Adipose Quality in Aging
This study will test the central hypothesis that fat within the muscle, or intramuscular adipose tissue (IMAT), exhibits elevated damage and pro-inflammatory s…
Virtual Function Anatomy (VFA)
This study will use magnetic resonance imaging (MRI) and ultrasound images to study how muscles, tendons, and bones work together to cause motion. The procedur…
Artificial Intelligence-Based Phenotyping of Health From Photographs - Healthy Volunteer Study
The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify …
The Baltimore Longitudinal Study of Aging (BLSA)
Background: \- The Baltimore Longitudinal Study of Aging (BLSA) is a clinical research program on human aging that began in 1958. Volunteers of different ages…
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging (BLSA)
Background: Some people experience cognitive decline as they age. That is, they lose memory, problem-solving, and other mental abilities. Amyloids are groups …
Driving Time and Left-Cheek Skin Hydration Asymmetry in Florida Residents: An Observational Study on Cumulative UVA Exposure Through Vehicle Side Windows
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female driver…
The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults
The goal of this clinical trial is to test the effects of MitoQ supplementation in older adults and frail older adults with physical dysfunction and/or cogniti…
A Prospective Observational Study of Facial Aging in Identical Twins Using Three-Dimensional Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age. Thi…
Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specificall…
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health - A Randomized, Double-Blind, Placebo-Controlled Study
The goal of this clinical trial is to learn if Quercefit® or Ubiqsome™ can improve markers of healthy aging, blood sugar control, and heart health in older adu…