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Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed…
RELAY: Repeated Magnetic Resonance Imaging Examinations to Analyze and Assess Your Cancer: A Prospective Study on the Use of Serial Magnetic Resonance Imaging in the Assessment of Changes During Treatment With Radiation Therapy
This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after…
Apple Health Study
The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information…
Balance Control and Recovery in Diabetes Peripheral Neuropathy
In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults ove…
Effects of NAD Restoration on Neurovascular Coupling in Community Dwelling Older Adults
Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to t…
Older Adult Traditional Balance Training vs Traditional Balance Training Plus Neck Strengthening
This study promotes greater understanding of factors impacting balance and how neck strength alters specific aspects of impaired balance. This study will help …
Optimizing Strength Training in Older Adults
The objective of the current study is to determine whether lifting lighter loads close to failure improves strength training adaptations and function in older …
Losing Specificity: the Role of the Locus Coeruleus in Age-related Distractibility
A growing body of research has highlighted the importance of frontal regions, at both the functional and structural levels, in age-related declines in attentio…
Investigating the Persisting Effects of a Single Dose of Psilocybin on Structural Plasticity in Healthy Older Adults
Participants in this study will undergo a series of non-invasive tests and activities designed to understand how a single dose of psilocybin might influence co…
Evaluating the Disease Modifying Potential of a Sleep Intervention on Alzheimer's Disease (AD) Biomarkers
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function …
Fatty Acid Modulation of Brain Function in Older Adults
In this crossover study, the investigtors will administer two experimental diets in a random order for one week, and each experimental diet will be preceded by…
Modulation of the Gut Microbiome by Dietary Fiber to Improve Calcium Absorption and Bone Health in Older Men
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for …