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Cardiorespiratory Fitness and Acute High-Intensity Exercise Effects on Brain and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a single session of high-intensity interval exercise (HIIT) affects cognitive performance and brain activit…
Integrative Medicine in Pain Management in Sickle Cell Disease: Assessing the Clinical Efficacy and Neurobiological Impact With Acupuncture, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairm…
Using Nicotine to Reverse Age-related Auditory Processing Deficits: Human Psychophysics and Electrophysiology
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered…
Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairm…
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnos…
Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV
The goal of this clinical trial is to examine 3 interventions designed to increase physical activity in older adults with HIV. We will examine 3 potential comp…
Robotically Assisted Anterior Eye Examinations for Acute Eye Care
The purpose of this study is to develop and test a robotically assisted imaging system for the front of the eye with a goal of helping eye care through the eme…
Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment
Tumor hypoxia is one of the physiological factors for treatment resistance and likely contributes to poor overall survival among patients with head and neck ca…
Effects of Ketogenic Diet on Alcohol Intoxication
The research study is being conducted to better understand the effects of ketosis on brain functioning and the acute effects of alcohol. Participants will be a…
Impacts of Rhythmic and Hypoxic Breathwork on EEG, Mood, Sleep, and Physiology
This project will study changes that occur during a short period of intensive daily slow-paced breathing and breath hold practice (i.e., "breathwork"). On the …
Quantitative Marrow Imaging, Marrow Reserve, And Clinical Outcomes In Patients Undergoing Radiotherapy For Hematologic And Related Disorders
To create a registry for people who are undergoing or previously underwent radiotherapy for hematologic or related disorders.