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Phase 2
Targeting Dopamine-Mediated Social Reward Sensitivity to Remediate Social Disconnection
This study seeks to understand if the medication pramipexole improves social connectedness and functioning in adults (ages 18-50) who experience anxiety or dep…
Anxiety DisordersAnxietyDepression+1 more
University of California, San DiegoNCT06269146
Observational
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
The purpose of this clinical trial is to answer the question: can the investigators predict which adults with social anxiety disorder (SAD) will successfully r…
Social Anxiety Disorder
Boston University Charles River CampusNCT05683223
Observational
A New Intervention for Implementation of Pharmacogenetics in Psychiatry
A 24-week, patient- and rater-blinded, two-arm, parallel-group controlled, and multi-centre randomized clinical trial (RCT) to establish the benefits of pharma…
Mood DisordersAnxiety DisordersPsychotic Disorders
Maastricht University Medical CenterNCT05656469
Phase 3
US, Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial of Fasedienol Nasal Spray for the Acute Treatment of Anxiety Induced by a Public Speaking Challenge in Adult Subjects With Social Anxiety Disorder, With an Open-Label Extension (PALISADE-4)
This U.S. Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute intranasal (i.n.) administration of Fasedienol Nas…
Social Anxiety Disorder (SAD)
VistaGen Therapeutics, Inc.NCT06615557