Browse studies

Find your next paid study

46 recruiting studies matching your filters

Phase I-II Study Evaluating HSV-tk + Valacyclovir Gene Therapy Combination With Radiotherapy and Chemotherapy for Recurrent Glioblastoma Multiforme

Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in recurrent glioblastoma multiforme.

Glioblastoma MultiformeAstrocytoma, Grade III

Estimated

~$10 – $7,500

David Baskin MDNCT03596086

Observational

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-CA, to improve the quality of life and cognitive function in Servi…

Brain CancerBrain TumorBrain Neoplasms+9 more

Estimated

~$10 – $6,250

Dartmouth-Hitchcock Medical CenterNCT06930846

Phase 2

A Phase 2 Trial of All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

This is a Phase II study of the combination of All-Trans Retinonic Acid (ATRA) and PD-1 inhibition (Retifanlimab) in patient with recurrent IDH-mutant glioma. …

GliomaIDH MutationAstrocytoma+1 more

Estimated

~$10 – $8,750

Stephen Bagley, MD, MSCENCT05345002

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma: Study Protocol for An International Multicenter Prospective Cohort Study (ENCRAM 2301)

Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site. To pursue maxim…

Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme of Brain+6 more

Estimated

~$10 – $750

Erasmus Medical CenterNCT06273176

Phase 2

Venous Thromboembolism Prevention in Outpatients With Glioma

This is an open label study of apixaban for venous thromboembolism prevention in patients with newly diagnosed grade 4 glioma.

GlioblastomaAstrocytomaVenous Thromboembolism

Estimated

~$10 – $6,250

University of Vermont Medical CenterNCT05683808

Phase 1

Phase I-II Study Evaluating HSV-tK + VALACYCLOVIR GENE THERAPY Combination With Radiotherapy and Chemotherapy for Newly Diagnosed Anaplastic Astrocytoma and Glioblastoma Multiforme.

Study to assess the safety and efficacy of HSV-tk (gene therapy), valacyclovir, radiotherapy and chemotherapy in newly diagnosed glioblastoma multiforme (GBM) …

GlioblastomaAnaplastic Astrocytoma

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT03603405

Phase 2

Phase II Trial of Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory Glioblastoma Multiforme, Anaplastic Astrocytoma, and Anaplastic Oligoastrocytoma

Primary brain tumors are typically treated by surgery, radiation therapy and chemotherapy, either individually or in combination. Present therapies are inadequ…

GlioblastomaAnaplastic AstrocytomaAnaplastic Oligoastrocytoma+6 more

Estimated

~$10 – $7,500

Northwell HealthNCT02800486

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma: Study Protocol for An International Multicenter Prospective Cohort Study (ENCRAM 2302)

Previous evidence has indicated that resection for recurrent glioblastoma might benefit the prognosis of these patients in terms of overall survival. However, …

GlioblastomaGlioblastoma MultiformeGlioblastoma, IDH-wildtype+5 more

Estimated

~$10 – $1,125

Jasper GerritsenNCT06283927

Phase 1

Phase I Study of Replication-Competent Adenovirus-Mediated Double Suicide Gene Therapy With Stereotactic Radiosurgery in Patients With Recurrent or Progressive High Grade Astrocytomas

The primary goal of this Phase I study is to determine the maximum tolerated dose of oncolytic adenovirus mediated double suicide-gene therapy in combination w…

Malignant Glioma of BrainAstrocytomaMalignant Astrocytoma+6 more

Estimated

~$10 – $6,250

Henry Ford Health SystemNCT05686798

Phase 1

Phase 1, Dose Escalation, Non-Randomized, Open Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells (AMSCs) for Recurrent Glioblastoma

This phase I trial tests the safety, side effects, and best dose of allogenic adipose-derived mesenchymal stem cells (AMSCs) in treating patients with glioblas…

Recurrent Glioblastoma, IDH-WildtypeRecurrent Astrocytoma, IDH-Mutant, Grade 4Astrocytoma, Grade IV

Estimated

~$10 – $6,250

Mayo ClinicNCT05789394