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71 recruiting studies matching your filters

Longitudinal Study for the Assessment of MRI Based Biomarkers as a Predictors of Clinical Endpoints in Pediatric Onset Autoimmune Liver Disease

Autoimmune liver diseases (AILD), which include Primary Sclerosing Cholangitis (PSC) and Autoimmune Hepatitis (AIH) are a common etiological factor for chronic…

Autoimmune Liver DiseaseAutoimmune HepatitisPrimary Sclerosing Cholangitis

Estimated

~$10 – $675

Children's Hospital Medical Center, CincinnatiNCT03178630

Observational

A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study

Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young ad…

Multiple SclerosisPathologic ProcessesDemyelinating Autoimmune Diseases, CNS+5 more

Estimated

~$10 – $6,250

University of Texas at AustinNCT07759115

Phase 3

A Phase 2/3, Randomized, Double-blind, Multicenter, Placebo-controlled Study of Inebilizumab in Participants With Autoimmune Hepatitis

The main objectives of this trial are to evaluate the safety and tolerability of inebilizumab in participants with autoimmune hepatitis (AIH) (Part 1) and to e…

Autoimmune HepatitisAIH

A Phase 1b/2a, Open-label Study of Velinotamig for the Treatment of Adults With Relapsing and Refractory Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

A Phase 1b/2a, open-label dose escalation and dose expansion study of subcutaneously (SC) administered velinotamig for the treatment of adults with relapsing a…

Immune Thrombocytopenia (ITP)Warm Autoimmune Hemolytic Anemia (WAIHA)

Estimated

~$10 – $8,750

Cullinan Therapeutics Inc.NCT07738822

Observational

Telehealth Music Therapy for Adults With Endocrine System Based Autoimmune Disease and a Depressive Disorder: An Intervention Development Study

The goal of this clinical trial is to explore if a telehealth music therapy intervention helps with quality of life, depression symptoms, anxiety symptoms. It …

Type 1 DiabetesHashimoto DiseaseGraves Disease+4 more

Estimated

~$10 – $6,250

Appalachian State UniversityNCT07413874

Observational

Informatics-Based Digital Intervention to Promote Safe Exercise in Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes - A Pilot Efficacy Study

The challenges of living with type 1 diabetes often stand in the way of getting enough exercise. Continuous blood sugar monitoring has revolutionized type 1 di…

Type 1 Diabetes (T1D)Latent Autoimmune Diabetes in Adult (LADA)Pancreatitis

Estimated

~$10 – $6,250

Yale UniversityNCT06967701

Phase 1

A Phase 1, Multicenter, Open-label Study of BMS-986515, Healthy Donor Allogeneic CD19-targeted Chimeric Antigen Receptor (CAR) T Cells, in Participants With Severe, Refractory Autoimmune Diseases

The purpose of this study is to determine the safety, tolerability, optimal dose, and preliminary efficacy of BMS-986515, a healthy donor (HD) allogeneic CD19-…

Refractory Autoimmune Diseases

Estimated

~$10 – $8,750

Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyNCT07115745

Phase 2

A Phase 2, Multicenter, Open-Label Study of Zolacabtagene Autoleucel (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Chronic Immune Thrombocytopenia (cITP) and Autoimmune Hemolytic Anemia (AIHA)

The purpose of this study is to evaluate the safety and efficacy of Zola-cel (BMS-986353), in participants with chronic immune thrombocytopenia (cITP) and auto…

Chronic Immune ThrombocytopeniaAutoimmune Hemolytic Anemia

Estimated

~$10 – $8,750

Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyNCT07603557

Natural History and Genetics of VEXAS Syndrome and Related Autoinflammatory Syndromes

This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders …

VEXAS SyndomeAutoinflammatory DiseaseAutoimmune Disease+1 more

Estimated

~$10 – $1,125

NYU Langone HealthNCT06004349

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic maligna…

Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+14 more

Estimated

~$10 – $1,125

Center for International Blood and Marrow Transplant ResearchNCT01351545

Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets

Background: Disorders of hearing instability (HI) are poorly characterized and ineffectively treated. HI can cause fluctuations in hearing thresholds and spee…

Meniere's DiseaseEnlarged Vestibular Aqueduct SyndromeAutoimmune Inner Ear Disease

Estimated

~$10 – $675

National Institute on Deafness and Other Communication Disorders (NIDCD)NCT04806282

Phase 2

A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a problem of the immune system. In people with APECED, the immune syste…

Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)Alopecia Areata

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT05398809