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Wake Forest University Health SciencesNCT05149573

Phase 1

A Double-Blind, Placebo-Controlled Study to Establish the Safety and Efficacy of Super-Concentrated, Freeze-Dried Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

The purpose of this study is to assess the safety and efficacy of super-concentrated, freeze-dried aloe vera capsules for treatment of interstitial cystitis.

Interstitial CystitisChronic Interstitial CystitisBladder Pain Syndrome

Wake Forest University Health SciencesNCT04734106

Phase 4

Urinary Tract Infection Prophylaxis In Intradetrusor OnabotulinumtoxinA Procedures: A Randomized Controlled Trial

Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life. Intradetrusor ona…

Overactive BladderBladder Pain Syndrome

Walter Reed National Military Medical CenterNCT06387329

Evaluation of Pulsed Radiofrequency Ablation of the Superior Hypogastric Plexus for Treatment of Bladder Pain Syndrome: A Case Series

Many women suffer from bladder pain syndrome (BPS). There are many treatments, but there is no one universally effective option. The goal of this clinical tria…

Bladder Pain Syndrome

Walter Reed National Military Medical CenterNCT06204874

Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome

Interstitial cystitis/bladder pain syndrome (IC/BPS) is estimated to affect 3.3 to 7.9 million women aged 18 years and older in the United States. The American…

Bladder Pain SyndromeFemale Sexual Dysfunction

Walter Reed National Military Medical CenterNCT06729151

~$10 – $750

Interstitial CystitisChronic Interstitial CystitisBladder Pain Syndrome

Investigation of the Effect of Simultaneous Pulsed Electromagnetic Field (PEMF) and Intravesical Heparin - Bupivacaine Cocktail Instillation for the Symptomatic Treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

The objective of this study is to test the idea that Pulsed Electromagnetic Field (PEMF) therapy will serve as a safe therapeutic modality that can effectively…

Wake Forest University Health SciencesNCT06013449

Phase 2

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multi-Center Single Dose Study to Evaluate the Safety and Effectiveness of VNX001 Compared to Placebo, and the Individual Components of Lidocaine, and Heparin in Subjects With Interstitial Cystitis/Bladder Pain Syndrome Who Have an Episode of Acute Bladder Pain of Moderate to Severe Intensity; The Engage 2024 Study

This is a Phase 2, prospective, randomized, double-blind, placebo-controlled, multi-center, single-dose, pharmacodynamic study designed to evaluate the efficac…

Interstitial CystitisBladder Pain Syndrome

Vaneltix Pharma, Inc.NCT05737121

~$10 – $8,750

Genetic Studies in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

Interstitial cystitis (IC), also called Bladder Pain syndrome (BPS) is a common condition with no known cause or cure. Twin studies and family accounts have su…

Interstitial CystitisBladder Pain Syndrome

Boston Children's HospitalNCT00389142

~$10 – $750

Chronic Interstitial CystitisBladder Pain SyndromePainful Bladder Syndrome+8 more

Mechanistic-Based Treatment of Interstitial Cystitis/Bladder Pain Syndrome

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.…

Vanderbilt University Medical CenterNCT06299683

Phase 2

A Phase 2b, Open Label, Single-Arm, Multi-Center, Multiple Dose, 14-Day Study to Evaluate the Safety, Efficacy, and Frequency of Intravesical Administration of VNX001 in Acute Treatment of Subjects With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Who Have an Episode of Acute Bladder Pain of Moderate to Severe Intensity

This is an open-label study that will enroll participants with Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS). The study will assess PRN (as needed) d…

Interstitial CystitisBladder Pain Syndrome

Vaneltix Pharma, Inc.NCT06394830

~$10 – $8,750

Urologic Chronic Pelvic Pain Syndrome (UCPPS)Interstitial CystitisBladder Pain Syndrome+4 more

A Brief, Transdiagnostic Cognitive Behavioral Treatment for Urological Chronic Pelvic Pain Syndrome: Processes, Predictions, Outcomes

The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagn…

State University of New York at BuffaloNCT05127616

Bladder Pain SyndromeInterstitial Cystitis

Acupuncture as First-line Therapy for Patients With Interstitial Cystitis/Painful Bladder Syndrome

The goal of this clinical trial is to learn if acupuncture in addition to behavioral changes can better treat in women with bladder pain syndrome (also known a…