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Phase 1
Pilot Study of Pre-emptive Anakinra for the Prevention of Severe Cytokine Release Syndrome in Children and Young Adults With B-Acute Lymphoblastic Leukemia Receiving Chimeric Antigen Receptor (CAR) T Cells
Objectives: The primary objective of this study will be to evaluate the impact of pre-emptive use of anakinra on the rate of severe cytokine release syndrome (…
B-Acute Lymphoblastic LeukemiaCAR-T Cell TherapyCytokine Release Syndrome+2 more
Ann & Robert H Lurie Children's Hospital of ChicagoNCT06703216
Observational
Nutrition OUtReach In Systems of Healthcare
Many children and adults receiving medical treatments have higher costs, which can make it harder for them to afford groceries. When someone can't afford enoug…
ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONAutologous Haemopoietic Stem Cell TransplantCAR-T Cell Therapy+1 more
University of Kansas Medical CenterNCT06802406
Phase 4
Seroconversion Following RSV Vaccination in Bone Marrow Transplant and CAR-T Patients
This study evaluates whether the RSV vaccine Abrysvo can produce an antibody response in patients with blood cancers who have previously received a hematopoiet…
CAR-T Cell TherapyRSV ImmunizationBone Marrow Transplant - Autologous or Allogeneic
The Cooper Health SystemNCT07296120
Observational
Coping Skills Training for Symptom Management and Daily Steps (Step Up)
The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable …
Hematopoietic Stem Cell TransplantCAR-T Cell Therapy
Duke UniversityNCT06575712