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740 recruiting studies matching your filters

A Multicenter, Prospective, Longitudinal Study to Assess Real-World Use and Outcomes After the Launch of TAR-200 for NMIBC in the US

The purpose of this study is to assess how well TAR-200 works in real-word by measuring the time taken from the first TAR-200 insertion to worsening of cancer …

Non-Muscle Invasive Bladder Neoplasms

Estimated

~$10 – $1,050

Janssen Research & Development, LLCNCT07309445

Phase 2

A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of SUN-627 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Impact on Measures of Neuroinflammation in the Central Nervous System in Participants With Non-Active Progressive Multiple Sclerosis (SPMS/PPMS)

The goal of this Phase 2 clinical trial is to investigate the safety and tolerability of SUN-627 in men and women aged 18-70 years old with a diagnosis of non-…

Primary Progressive Multiple SclerosisPrimary Progressive MSPrimary Progressive Multiple Sclerosis (PPMS)+6 more

Estimated

~$10 – $8,750

Sundance Biosciences, Inc.

Phase 3

A Phase 3, Single-Arm, Open-Label, Long-Term Extension Study To Evaluate The Safety And Efficacy Of Enpatoran In Participants With Active Cutaneous Manifestations Of Lupus Erythematosus With Or Without Systemic Disease Receiving Standard Of Care [Elowen-LTE]

The purpose of this study is to evaluate the long-term safety and efficacy of orally administered enpatoran in participants with cutaneous manifestations of lu…

Systemic Lupus Erythematosus (SLE)Cutaneous Lupus Erythematosus (CLE)

Estimated

~$10 – $8,750

EMD Serono Research & Development Institute, Inc.NCT07840287

Observational

Understanding the Impact of Meal Timing on Neurological Health in Adults With Multiple Sclerosis

The goal of this clinical trial is to learn if the time an individual eats each day impacts neurological health in people with multiple sclerosis. The main que…

Multiple Sclerosis

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07475377

Phase 1

A Pilot Study of HIF-Mediated Gene Expression Changes in Casdatifan-Treated Refractory Renal Cell Carcinoma

This is a single-institution, pilot study of oral casdatifan, a selective HIF-2α inhibitor, in patients with metastatic clear cell renal cell carcinoma refract…

Refractory Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell Carcinoma

Estimated

~$10 – $6,250

Vanderbilt-Ingram Cancer CenterNCT07748988

Phase 1

Evaluation of Haploidentical, Donor-Derived B Lymphocyte Infusions in Patients With Amyotrophic Lateral Sclerosis

This study is testing whether giving people with ALS specially matched immune cells called B cells from a related donor is safe. Up to 10 participants will eac…

ALS - Amyotrophic Lateral Sclerosis

Estimated

~$10 – $7,500

Mark PoznanskyNCT07838389

Phase 2

A Randomized, Double-Blinded, Placebo-Controlled, Phase 2, Parallel-Group Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Efgartigimod PH20 SC in Adult Participants With Systemic Sclerosis

The main purpose of this study is to evaluate the effect and safety of efgartigimod PH20 SC compared to placebo in adults with systemic sclerosis. The study co…

Systemic Sclerosis (SSc)

Estimated

~$10 – $7,500

argenxNCT06655155

Clinical Assessment and Targeted Imaging to Characterize High-Risk Atherosclerotic Cardiovascular Disease of Survivors in the St. Jude Lifetime Cohort (SJLIFE)

Childhood cancer survivors are at increased risk for premature atherosclerotic cardiovascular disease (ASCVD) due to cancer treatment-related exposures, includ…

Atherosclerotic Cardiovascular Disease

Estimated

~$10 – $750

St. Jude Children's Research HospitalNCT07594392

Natural History of Inflammatory Muscle Diseases

Objective: To collect information and biospecimens (such as blood, muscle, and skin samples) that will be used to research causes and treatments of inflammato…

Inflammation In Skeletal Muscle

Estimated

~$10 – $675

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT05738824

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Effect of Muvalaplin on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) Who Have Had a Prior Atherosclerotic Cardiovascular Event or Are at Risk for a First Atherosclerotic Cardiovascular Event

The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovas…

Elevated Lp(a)Atherosclerotic Cardiovascular Disease (ASCVD)

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07157774

Phase 2

An Open-label, Single-Arm, Phase 2 Study to Evaluate Enfortumab Vedotin Plus Pembrolizumab for Bladder Preservation in Participants With Muscle-invasive Bladder Cancer (EV-209)

People with a type of bladder cancer called muscle-invasive bladder cancer have cancer that has spread into the muscle wall of the bladder. The standard treatm…

Muscle-invasive Bladder Cancer

Estimated

~$10 – $8,750

Astellas Pharma Global Development, Inc.NCT07475806

Phase 3

A Phase 3, Double-blinded, Vehicle-controlled Trial to Investigate the Efficacy and Safety of Twice Daily Delgocitinib Cream in Adult Participants With Lichen Sclerosus During a 12-Week Initial Treatment Period Followed by a 40-Week Continuation Treatment Period

The main objective of the study is to evaluate the efficacy of twice daily applications of delgocitinib cream compared with cream vehicle in the treatment of a…

Lichen Sclerosus

Estimated

~$10 – $8,750

LEO PharmaNCT07335588