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Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders: A Randomized, Double-blind, Placebo-controlled, Parallel-group, MRI Study

This research study evaluates the effects of an FDA-approved medication Gabapentin in individuals with Bipolar Disorder who smoke marijuana. Participants in th…

Bipolar DisorderCannabis UseSchizoaffective Disorder, Bipolar Type+5 more

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT05064319

Examining the Role of Functional Social Support Subtypes for Self-Management Capacity Among Individuals With COPD

This observational study aims to examine how different types of functional social support (emotional/informational, tangible, affectionate, and positive social…

Chronic Obstructive Pulmonary Disease (COPD)

Estimated

~$10 – $750

Medical University of South CarolinaNCT07353034

Phase 2

Peroxisome Proliferator-Activated Receptor Agonists to Prevent Primary Sclerosing Cholangitis Recurrence After Liver Transplantation

This study aims to determine the efficacy of 36 months once-daily fenofibrate in preventing clinically-detectable recurrence of primary sclerosing cholangitis …

Primary Sclerosing CholangitisLiver Transplant, ComplicationsPSC+1 more

Estimated

~$10 – $6,250

Mayo ClinicNCT06905054

Observational

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

This study is following up on previous studies that have demonstrated that geriatric subjects respond different to ultraviolet B (UVB) light than young subject…

Actinic KeratosesAgingNon-Melanoma Skin Cancer

Estimated

~$10 – $6,250

Wright State UniversityNCT03906253

Observational

Goal Setting to Promote Physical Activity Adherence in Midlife to Reduce Risk of Alzheimer's Disease and Related-Dementias: A Randomized Mechanistic Proof-Of-Concept Trial

Engaging in regular physical activity during midlife is a key lifestyle behavior associated with reduced risk for Alzheimer's disease and related dementias (AD…

Physical ActivityExercise

Estimated

~$10 – $6,250

Arizona State UniversityNCT05980052

Phase 1

A Phase I Study to Evaluate the Safety of Escalating Doses of Lymphodepleting Conditioning Chemotherapy Prior to CD19 Chimeric Antigen Receptor T Cells in Subjects With Relapsed/Refractory Diffuse Large B-cell Lymphoma

This phase I trial evaluates the best dose, possible benefits and/or side effects of fludarabine and cyclophosphamide with or without rituximab before CD19 chi…

Recurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma

Estimated

~$10 – $6,250

University of California, DavisNCT05052528

Phase 2

NAC-REPAIR: N-Acetylcysteine-facilitated Redox-Immune Modulation for Post-surgical Analgesia and Injury Recovery

This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce p…

Carpal Tunnel SurgeryTrigger Finger DisorderDe Quervain Syndrome+6 more

Estimated

~$10 – $6,250

University of ArizonaNCT07227649

Phase 2

Phase 2 Study of Glofitamab and Gemcitabine and Oxaliplatin (Glofit-GemOx) Bridging to Lisocabtagene Maraleucel in Relapsed/Refractory Aggressive B-cell Lymphomas

The goal of this clinical trial is to assess the clinical efficacy of bridging therapy with glofitamab/gemcitabine/oxaliplatin (Glofit-GemOx) followed by lisoc…

LymphomaB-cell LymphomasRelapsed/Refractory Large B-cell Lymphoma+1 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT07711483

Phase 1

Phase I/II Study of Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

This is an open-label, phase I/II study of duvelisib in combination with Venetoclax for patients with relapsed/refractory NHL. Duvelisib is an FDA approved, ma…

T-cell-prolymphocytic LeukemiaCutaneous T-Cell Lymphoma Refractory

Estimated

~$10 – $6,250

Jonsson Comprehensive Cancer CenterNCT06810778

CHORUS: Comprehensive HHT (Hereditary Hemorrhagic Telangiectasia) Outcomes Registry of the United States

The Comprehensive HHT Outcomes Registry of the United States (CHORUS) is an observational registry of patients diagnosed with Hereditary Hemorrhagic Telangiect…

Hereditary Hemorrhagic TelangiectasiaArteriovenous MalformationsTelangiectasia+4 more

Characterizing Daily Activity and Cognition in Older Adults

The purpose of this study is to characterize the relationships between changes in cognitive functioning across the day and patterns of physical activity in old…

Physical ActivityCognitionAging

Estimated

~$10 – $6,250

Wake Forest UniversityNCT07710339

Observational

Understanding and Improving Access to Section 504 Among Students With Disabilities

The goal of this training program is to learn if the intervention (i.e., training program) can improve access to Section 504 among students with disabilities a…

Students With Disabilities and/or Family Members With Students With Disabilities That Have a Section 504 Plan

Estimated

~$10 – $6,250

Vanderbilt UniversityNCT07710300