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4,344 recruiting studies matching your filters

Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair Cases

The purpose of the study is to evaluate the safety and efficacy of devices used in patients undergoing fetoscopic neural tube defect repair.

Neural Tube Defects

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Michael A BelfortNCT05672849

Phase 2

A Phase 2, Open-Label, Multicenter, Randomized Study Evaluating Neoadjuvant Therapy Targeting the Adenosine Immunosuppressive Pathway in Combination With Immune Checkpoint Blockade and Radiation Therapy in Patients With Advanced PANCreatic Ductal Adenocarcinoma Who Are Candidates for Surgical Resection

The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simultaneously …

Pancreatic Ductal Adenocarcinoma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Gulam ManjiNCT06048484

Preserved vs. Reduced Ejection Fraction Biomarker Registry and Precision Medicine Database for Ambulatory Heart Failure Patients (PREFER-HF) Study

In this single-center, longitudinal observational study, we will comprehensively examine clinical characteristics, proteomic, metabolomic, genomic and imaging …

Heart Failure With Normal Ejection FractionHeart Failure With Reduced Ejection FractionHeart Failure, Right Sided+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT03480633

Phase 2

A Single Arm Phase 2 Study of Y-90 SIRT in Combination With Durvalumab (MEDI 4736) and Gemcitabine/Cisplatin in Locally Advanced, Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

This trial is designed to study a combination of interventions (chemotherapy, immunotherapy, and radiation) as a potential new treatment for bile duct cancer t…

Bile Duct CancerCholangiocarcinomaCholangiocarcinoma Non-resectable+2 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Beth Israel Deaconess Medical CenterNCT05655949

Assessment of Changes in Normal and Pathological Immune Factors in Patients Undergoing Plasma Exchange

Patients who have immune mediated diseases commonly undergo plasma exchange (PLEX) procedures to remove pathological substances, typically believed to be antib…

Antibody-mediated RejectionNMO Spectrum DisorderTTP+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Charles M KnudsonNCT05004493

Observational

Mitigating Opioid Use Disorder Risk With Enhanced Opioid Sparing Pain Relief for Wisdom Teeth Extractions With a Novel Nanotechnology

This is a randomized (1:1), placebo-controlled clinical trial that will examine the feasibility and effectiveness of a 2-day application of the NeuroCuple devi…

Wisdom TeethWisdom Teeth Extraction or Jaw Implant

Estimated

~$10 – $1,125

Actual pay is set by the research site.

nCap MedicalNCT07461506

Phase 1

A Phase I/IIa Randomized Clinical Trial to Evaluate the Efficacy of EGFR-targeted, PNU-159682-packaged Nanocells & Glycolipid-Packaged Nanocells in Combination With Gemcitabine & Nab-paclitaxel in Metastatic Pancreatic Ductal Adenocarcinoma

The purpose of this study is to evaluate the safety and tolerability and overall survival (OS) of E-EDV-D682/GC in combination with gemcitabine and nab-paclita…

Pancreatic Cancer, MetastaticPDAC - Pancreatic Ductal Adenocarcinoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Engeneic Pty LimitedNCT07049055

Phase 2

A Prospective, Multi-Center Study to Evaluate the Safety and Effectiveness of the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections

This study is being conducted to evaluate the safety and effectiveness of the REMEDY SPECTRUM IM Spacer Nail in the treatment of ankle-related infections. The …

Periprosthetic Joint Infection

Estimated

~$75 – $2,800

Actual pay is set by the research site.

OsteoRemedies, LLCNCT06428448

Home Reported Outcomes in PNH: A Mobile App-Based, Prospective, Observational Program to Evaluate Disease Burden and Treatment Patterns in Paroxysmal Nocturnal Hemoglobinuria in the US

The study aims to longitudinally capture the full spectrum of symptoms, treatment utilization, and overall Health-Related Quality of Life (HRQoL) experienced b…

Paroxysmal Nocturnal Hemoglobinuria

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT06411626

Phase 1

Safety and Efficacy of Expanded KIR-HLA Mismatched Natural Killer Cell Immunotherapy (AdaptNK) for High-Risk Myeloid Diseases as Bridge to Allogeneic Hematopoietic Stem Cell Transplantation

This is a multi-institutional Phase I/II study of an allogeneic KIR-HLA mismatched NK cell infusion (AdaptNK) and a short course of subcutaneous interleukin-2 …

Relapsed Adult AMLRefractory AMLAcute Myelogenous Leukemia

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Masonic Cancer Center, University of MinnesotaNCT07591649

Observational

Implementation Science-Guided Pilot Study of Trauma-Focused Cognitive Behavioral Therapy for Autistic Youth in Community Mental Health Settings

Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms followin…

Autism Spectrum DisorderPTSD and Trauma-related SymptomsAutism+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Dartmouth-Hitchcock Medical CenterNCT07420478

Phase 1

Phase 1/2 Study of IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

This is an open label, Phase 1/2, first-in-human, multiple ascending dose, and dose-expansion study of IDP-023 administered as a single agent and in combinatio…

NHLMultiple MyelomaBlood Cancer+4 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Indapta Therapeutics, INC.NCT06119685