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4,344 recruiting studies matching your filters

A Phase I/Ib Dose Escalation Trial of Futibatinib in Combination With Paclitaxel/Ramucirumab in Second Line Confirmed Locally Advanced/Unresectable Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

This phase I trial tests the safety, side effects and best dose of futibatinib with paclitaxel and ramucirumab for the treatment of patients with gastric, gast…

Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+13 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Northwestern UniversityNCT07594548

Phase 1

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

This research is being done to investigate a treatment regimen of Irinotecan, Temozolomide, and Sargramostin, and an immunotherapy called Naxitamab and whether…

NeuroblastomaNeuroblastoma RecurrentRelapsed Neuroblastoma+1 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Steven DuBois, MDNCT07027748

Observational

An Effectiveness Trial of WINGS+PrEP: a Syndemic mHealth Intervention to Increase PrEP Uptake Among Women Impacted by Heavy Alcohol Use and Partner Violence in the Criminal Legal System

(Effectiveness Aim 1) To test the comparative effectiveness of PreP for WINGS versus PrEP alone on primary outcomes of increasing PrEP initiation measured by s…

HIV InfectionsAlcohol Use DisorderViolence, Gender-Based

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06853314

Observational

Electrical Rectal Stimulation to Promote Bowel Emptying After Spinal Cord Injury

The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogen…

Neurogenic Bowel Dysfunction

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06078176

Phase 1

PRISMatic: A Phase 1b Randomized, Double-Armed, Parallel-Group, Placebo-Controlled Trial of Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Twenty healthy adults (≥21 years old) will be enrolled to evaluate the efficacy of a single oral dose of psilocybin (25 mg) administered with or without pretre…

Mood (Psychological Function)Well BeingMood+1 more

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Johns Hopkins UniversityNCT07610135

Observational

Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal…

AgingBlood PressureEndothelial Dysfunction+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, BoulderNCT05000515

A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy

This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions…

DCISStage 0 Breast CancerDuctal Breast Carcinoma In Situ

Estimated

~$10 – $1,125

Actual pay is set by the research site.

PreludeDxNCT03448926

Phase 2

A Phase 2b, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

This study has 3 treatment phases, a 12-Week Induction Phase, a 40-Week Maintenance Phase, and a 48-Week Extension Phase. The objective is to evaluate the eff…

Moderately to Severely Active Crohn Disease

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Abivax S.A.NCT06456593

Phase 1

A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses

The goal of this clinical trial is to test two investigational COVID-19 booster vaccines, called CoTend-s3BXBB and CoTend-BXBB, in healthy volunteers ages 40-6…

COVID-19SARS-CoV-2 Infection

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Kara ChewNCT06810934

Phase 1

FIERCe: FOLR1 Immune Effector Cell Therapy Against Advanced Osteosarcoma

This phase I trial tests the safety, side effects, and best dose of FH-FOLR1 ST chimeric antigen receptor (CAR) T cells and how well they work in treating pati…

Advanced OsteosarcomaRecurrent OsteosarcomaRefractory Osteosarcoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT07227571

Phase 2

Endoscopic Ultrasound Radiofrequency Ablation and Immunotherapy Pembrolizumab for Locally Advanced Unresectable and Metastatic Pancreatic Duct Adenocarcinoma; a Phase II Trial PANcreas CAncer RaDIofrequeNcy AbLation

The purpose of this study is to perform a pilot phase II trial to evaluate the safety and efficacy of combined EUS-RFA, chemotherapy, and systemic immunotherap…

Pancreatic Ductal Adenocarcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06831136

Phase 2

A Randomized, Double-blind, Placebo-controlled, Dose-escalation Study Evaluating the Efficacy of Two Doses of Duloxetine & Amitriptyline in Subjects With Refractory Chronic Cough

This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with refractory…

Refractory Chronic Cough

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT05110144