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4,350 recruiting studies matching your filters

A Single-Arm, Open-Label, Multicenter, Phase 1b/2 Study Evaluating the Safety and Efficacy of AUTO1 (Obecabtagene Autoleucel [Obe-cel]) in Pediatric Patients With CD19-positive Relapsed/Refractory (R/R) B Cell Acute Lymphoblastic Leukemia (B ALL) or R/R Aggressive Mature B Cell Non-Hodgkin Lymphoma (B NHL).

This is a Phase 1b/2 study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting cluster of dif…

Relapsed or Refractory B Cell Acute Lymphoblastic LeukemiaRelapsed or Refractory B Cell Non-Hodgkin Lymphoma

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Autolus LimitedNCT06173518

Phase 3

Randomized Clinical Trial of Personalized vs Standard of Care Treatment for Helicobacter Pylori Eradication Among Veterans: "VA Eradicate HP"

The primary objective of this study is to compare the Helicobacter pylori (H. pylori) eradication rate following empiric bismuth-based quadruple therapy (BQT) …

Helicobacter Pylori

Estimated

~$50 – $1,350

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07104318

Phase 2

Human Craniomaxillofacial Allotransplantation

Background: The human face is critically important for breathing, eating, seeing, and speaking/ communicating, but its most important job may be to look like a…

Facial InjuriesTraumatic Wounds and InjuriesCraniofacial Injuries+3 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Johns Hopkins UniversityNCT01889381

Phase 3

A Phase III Randomized Trial of Dose Escalated Radiation in Locally Advanced Pancreas Cancer (LAPC) Patients (LAP100)

This phase III trial compares the effect of dose-escalated radiation therapy to usual care in patients with locally advanced unresectable pancreatic ductal ade…

Locally Advanced Unresectable Pancreatic Ductal AdenocarcinomaStage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8+1 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

NRG OncologyNCT06958328

Phase 1

An Open-Label, Multicenter, Multi-arm Phase 1 Study Evaluating the Safety and Pharmacokinetics of ADU-1805 in Adults With Advanced Solid Tumors

This first-in-human, open-label, multicenter, multi-arm dose-escalation study is designed to evaluate the safety, PK, and PD of ADU-1805, an anti- SIRPα monocl…

Solid Tumor, AdultMetastatic Solid TumorRefractory Cancer+4 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Sairopa B.V.NCT05856981

Phase 3

DESTINY-Biliary Tract Cancer-01: A Phase 3 Study of Trastuzumab Deruxtecan (T-DXd) and Rilvegostomig Versus Standard-of-Care Gemcitabine, Cisplatin, and Durvalumab for First Line Locally Advanced or Metastatic HER2-expressing Biliary Tract Cancer

The purpose of this study is to measure the efficacy and safety of T-DXd with rilvegostomig or T-DXd monotherapy compared with gemcitabine plus cisplatin and d…

Biliary Tract Cancer

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AstraZenecaNCT06467357

Phase 4

Optimizing Anesthesia to Prevent Postoperative Cognitive and Functional Decline in Older Adults: A Randomized Controlled Trial

Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (I…

Neurocognitive DisordersAnesthesiaPost-operative Delirium+1 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT06036095

Phase 4

Comparing the Efficacy and Safety of Holmium Laser Lithotripsy Versus Electrohydraulic Lithotripsy for the Treatment of Difficult Choledocholithiasis and Pancreatic Duct Stones: A Randomized Controlled Trial

The goal of this clinical trial is to learn if a low-power holmium laser works to treat large and/or difficult bile duct or pancreatic duct stones in adults. I…

CholedocholithiasisPancreatic Duct Stone

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Rush University Medical CenterNCT07418112

Observational

Substance Use Treatment and Access to Resources (STARS) Project

This study is evaluating a randomized clinical trial and a quasi-experimental observational study combined. Pregnant women with substance abuse issues are refe…

Substance Use DisordersPregnancy RelatedChild Neglect

Estimated

~$10 – $750

Actual pay is set by the research site.

University of OklahomaNCT04459000

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and h…

Heart; Dysfunction Postoperative, Cardiac SurgeryGenetic Predisposition to DiseaseAtrial Fibrillation+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT01258231

Observational

Evaluating a Respiratory Oxygen Adherence Monitor for COPD Patients With Long-term Oxygen Therapy

The goal of this clinical trial is to test a device called "ROAM" that is being developed to see how patients with chronic obstructive pulmonary disease (COPD)…

COPDCOPD - Chronic Obstructive Pulmonary Disease

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Barron Associates, Inc.NCT06874101

Observational

Music Therapy to Improve Dental Procedure Tolerance and Reduce Distress in Adults With Intellectual and Developmental Differences

Adults with intellectual and developmental differences may experience behavioral distress, sensory sensitivity, and difficulty tolerating dental procedures. Th…

Intellectual and Developmental DifferencesDental Anxiety

Estimated

~$10 – $750

Actual pay is set by the research site.

University of RochesterNCT07806201