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Multisite Implementation of COMPRENDO (ChildhOod Malignancy Peer REsearch NavigatiOn) to Improve Participation of Hispanic Children in Cancer Clinical Trials

COMPRENDO (ChildhOod Malignancy Peer Research NavigatiOn) is a multi-site randomized clinical trial (RCT) that uses a Hybrid Type 1 design, to test the effects…

Pediatric Cancer

Estimated

~$10 – $6,250

University of California, San DiegoNCT06055296

Phase 2

Reiki-Brachy: An Interventional Treatment Trial Using Reiki Therapy to Improve Symptoms Associated With Brachytherapy in Patients With Gynecological Malignancies

The goal of this open label, randomized, controlled clinical trial is to assess the benefits of providing Reiki therapy to subjects receiving their first brach…

Gynecologic NeoplasmBrachytherapyTherapeutic Touch+4 more

Estimated

~$10 – $6,250

University of UtahNCT05979610

Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types

ClearNote Health is developing a test from whole blood for the early detection of multiple cancers. The goal of this study is to employ genomics, epigenomics a…

Diagnosis of Cancer of Various Organs

Estimated

~$10 – $1,125

ClearNote HealthNCT03869814

Phase 2

A Randomized Phase 2 Study Assessing the Efficacy and Safety of Olvimulogene Nanivacirepvec Followed by Platinum-doublet Chemotherapy + Physician's Choice of Immune Checkpoint Inhibitor Compared With Docetaxel in Patients With NSCL Cancer After First Progression While on Front-line Immune Checkpoint Inhibitor-based Maintenance

This Phase 2, open-label, randomized study in non-small-cell lung cancer (NSCLC) is designed to evaluate the efficacy and safety of an intravenously delivered …

Advanced Non-squamous Non-small-cell Lung CancerAdvanced Squamous Non-Small Cell Lung CarcinomaMetastatic Non-squamous Non Small Cell Lung Cancer+5 more

Estimated

~$10 – $8,750

Enhancing Skin Appearance and Quality of Life in Breast Cancer Survivors on Aromatase Inhibitor Therapy

This study evaluates changes in skin quality and self-esteem among breast cancer patients who are initiating aromatase inhibitor therapy.

Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8+4 more

Estimated

~$10 – $750

Mayo ClinicNCT06401889

Phase 1

Administration of T Cells Expressing B7-H3 Specific Chimeric Antigen Receptors (CAR) and Containing the Inducible Caspase 9 Safety Switch in Subjects With Recurrent Platinum Resistant Epithelial Ovarian Cancer

The purpose of this study is to test the safety and tolerability of using a new treatment called autologous T lymphocyte chimeric antigen receptor cells agains…

Ovary NeoplasmOvarian CancerEpithelial Ovarian Cancer+1 more

Estimated

~$10 – $6,250

UNC Lineberger Comprehensive Cancer CenterNCT06305299

Phase 2

A Phase II Pilot Trial of ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer Patients ("ABBY")

This is a Phase II randomized, controlled, open label breast cancer clinical trial. 66 patients will be enrolled. The drugs being studied are hydroxychloroquin…

Breast Cancer

Estimated

~$10 – $6,250

Abramson Cancer Center at Penn MedicineNCT04523857

Observational

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Cancer Risk Stratification of Pulmonary Nodules

This is a pragmatic clinical trial that will study the effect of a radiomics-based computer-aided diagnosis (CAD) tool on clinicians' management of pulmonary n…

Lung CancerPulmonary Nodule, Solitary

Estimated

~$10 – $6,250

Abramson Cancer Center at Penn MedicineNCT05968898

A Comprehensive Breast Cancer Survivorship Biorepository

This study collects blood samples as well as clinical and self-report data from stage I-III breast cancer survivors to create a biorepository for future use. T…

Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+1 more

Estimated

~$10 – $750

University of Southern CaliforniaNCT05786664

Observational

Online Training After Cancer (On-Trac): Developing An Online Intervention for Cancer Survivors Managing Anxiety

This study is evaluating On-Trac (Online Training After Cancer), an online educational intervention to teach adult cancer survivors strategies to address anxie…

CancerSurvivorshipAnxiety

Documented

Up to $90

Dana-Farber Cancer InstituteNCT07305740

Phase 1

An Open-label, Navigational Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses

This is a prospective, open-label navigational investigation designed to evaluate the feasibility of using molecular profile-based evidence to determine indivi…

Cancer

Estimated

~$10 – $6,250

Medical College of WisconsinNCT05674825

Observational

Menstrual Cup-based Endometrial Collection as an Alternative to Endometrial Biopsy in Lynch Syndrome Patients

Study Goal: This pilot study wants to find out if using a menstrual cup can be a good, non-invasive way to collect samples from the lining of the uterus (call…

Endometrial CancerLynch SyndromeScreening+1 more

Estimated

~$10 – $7,500

Jessica D. St. Laurent, MDNCT07220239