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The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles
This study will examine the pharmacokinetics and pharmacodynamics of delta-9-tetrahydrocannabinol (THC)-infused chocolates, gummies, and drinks. Healthy adults…
Pilot Study of Psilocybin-assisted Treatment for Cannabis Use Disorder
This pilot study will evaluate the therapeutic potential of psilocybin in people with Cannabis Use Disorder (CUD). This study will examine the impact of psiloc…
Acute Effects of Cannabis on Cognition and Affect
This study will examine how a moderate dose of THC affects mood, stress responses, and cognitive functioning in regular cannabis users. The study uses a double…
Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance
The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this…
Exploring the Antecedents and Consequences of Cannabis Use in the Context of Coping: An Experimental Study
The purpose of the study is to better understand the effects of cannabis in relation to mental and physical states including its relationship with mood, cognit…
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects o…
Pregnenolone as a Treatment for Cannabis Intoxication
The present study will characterize the ability of pregnenolone to reverse the acute intoxication and associated symptoms of cannabis. Healthy adults with a hi…
Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study
The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health pro…
Alcohol and Cannabis Use Among Assault-Injured Emerging Adults
This study aims to improve a short motivational conversation to better help young adults who were injured in assaults and also use alcohol or cannabis. Researc…
Sex Differences in Neurobehavioral Response to Acute THC in Adults With Cannabis Use Disorder
This study investigates sex differences in reward processing following acute THC administration in adults with cannabis use disorder (CUD). Using multimodal ne…
Acute Effects of Sequential Nicotine Vaping on the Pharmacokinetic and Pharmacodynamic Properties of Vaped THC: A Double-Blind, Placebo-Controlled, Randomized Within-Subject Crossover Study
This clinical trial assesses differences in the delivery of THC to the bloodstream depending on whether nicotine vapes are used before or after THC. While ther…
Feasibility/Acceptability of a Brief Motivational Intervention Integrating Online Personalized Feedback & Tailored Text Messages for Frequent/High-Intensity Cannabis Use in Post-Legalization Landscape
The study aims to develop a novel brief motivational mobile health (mHealth) intervention for frequent and/or high-intensity cannabis use for non-collegiate yo…