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6 recruiting studies matching your filters

A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of participants aged 10 to 17 years w…

Chondral DefectOsteochondritis Dissecans (OCD)Articular Cartilage Defect+1 more

Estimated

~$10 – $8,750

Vericel CorporationNCT03588975

Phase 3

A Prospective, Open-label, Randomized, Concurrent Active-controlled, Longitudinal, Multicenter, Phase 3 Clinical Study of the Safety and Efficacy of MACI in Patients With Symptomatic Chondral or Osteochondral Lesions of the Talus (MASCOT)

The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimul…

Chondral DefectArticular Cartilage Defect

Estimated

~$10 – $8,750

Vericel CorporationNCT06915233

Observational

Pivotal, Prospective, Randomized, Controlled, Multicenter Clinical Trial of BioPoly® Partial Resurfacing Knee Implant for Treatment of Focal Cartilage Lesions of the Distal Femur

The goal of this randomized controlled clinical trial is to demonstrate the safety and effectiveness of the BioPoly® Partial Resurfacing Knee Implant for the t…

Knee Pain ChronicKnee OsteoarthritisCartilage Damage+3 more

Estimated

~$10 – $8,750

BioPoly LLCNCT06915363

Prospective PROMs Outcomes in Arthroscopic Acetabular Labral Repair With and Without Application of Platelet-Rich Plasma (PRP) Harvested From the Body of the Ilium

Femoro-acetabular impingement is a well known cause of damage to the acetabular labrum and chondrolabral junction. Additionally, it has been proposed that disr…

Acetabular Labrum TearFemoro Acetabular ImpingementChondral Defect+2 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT03909139

Observational

A Prospective, Open Label, Single-Arm, Multi-Center Study Evaluating Cryopreserved Osteochondral Allograft Cores for the Treatment of Osteochondral Lesions in the Knee

The primary objective of this study is to obtain evidence of the effectiveness of Cryopreserved Osteochondral Allograft Core in the treatment of osteochondral …

Osteochondral Defect

Estimated

~$10 – $7,500

AlloSourceNCT06216756

Phase 3

Effect of Platelet-Rich Plasma, Platelet-Poor Plasma, & Bone Marrow Aspirate Concentrate Application on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies: A Prospective Randomized Controlled Trial

The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral p…

Acetabular Labrum TearFemoro Acetabular ImpingementChondral Defect+1 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06003101