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16 recruiting studies matching your filters
Phase 1
PET Imaging of Synaptic Density Combined With Neuroimmunologic Measures to Reveal Mechanisms of HIV Neuropathogenesis During ART
The purpose of this study is to longitudinally characterize and evaluate changes in synaptic density in the brain using novel positron-emission tomography (PET…
HIV Associated Neurocognitive DisorderHIV DementiaHIV Encephalitis+1 more
Yale UniversityNCT05586581
Observational
Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders (ENHANCE)
The goal of this clinical trial is to compare the Hospital Elder Life Program (HELP) with a family-augmented version of HELP (FAM-HELP), that includes family m…
DeliriumNeurocognitive DisordersMild Cognitive Impairment+7 more
University of MichiganNCT05929703
Phase 4
Optimizing Anesthesia to Prevent Postoperative Cognitive and Functional Decline in Older Adults: A Randomized Controlled Trial
Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (I…
Neurocognitive DisordersAnesthesiaPost-operative Delirium+1 more
Oregon Health and Science UniversityNCT06036095
Observational
Real-world and Innovative Multimodal Prediction and Prevention of Postoperative Mortality and Multi-morbidities
This study will contribute to creating a prospective and automated preoperative risk assessment algorithm for predicting 30-day mortality, major adverse cardia…
DementiaPostoperative Delirium (POD)Postoperative Neurocognitive Disorder+3 more
University of PittsburghNCT06042413