Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates p…

Primary Progressive AphasiaDementiaDementia, Frontotemporal+11 more

~Estimated

~$10 – $7,500

Stephanie GrassoNCT05741853

Phase 2

Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease

This is a randomized, double-blinded, placebo-controlled, crossover trial that aims to 1) determine the efficacy of THC-free cannabidiol (CBD oil) in reducing …

Alzheimer DiseaseDementiaMajor Neurocognitive Disorder With Aggressive Behavior

~Estimated

~$10 – $7,500

Eastern Virginia Medical SchoolNCT04436081

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside on Bioenergetic Metabolism, Oxidative Stress, and Cognition in Mild Cognitive Impairment and Mild Alzheimer's Dementia

This project's main goal is to use state-of-the-art passive sensing techniques to identify digital biomarkers that relate to bioenergetic changes in the brain …

Alzheimer DiseaseDementia AlzheimersDementia+7 more

~Estimated

~$10 – $750

Mclean HospitalNCT05245903

Phase 4

Optimizing Anesthesia to Prevent Postoperative Cognitive and Functional Decline in Older Adults: A Randomized Controlled Trial

Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (I…

Neurocognitive DisordersAnesthesiaPost-operative Delirium+1 more

~Estimated

~$10 – $6,250

Oregon Health and Science UniversityNCT06036095

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