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54 recruiting studies matching your filters

A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This…

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in…

Inflammatory Bowel DiseasesCrohn's Disease

Estimated

~$10 – $8,750

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)NCT06226883

Phase 3

A Master Protocol for a Phase 3, Multicenter, Open-label, Long-term Extension Study to Evaluate the Long-term Efficacy and Safety of Mirikizumab in Children and Adolescents With Moderate-to-severe Ulcerative Colitis or Crohn's Disease

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (…

Ulcerative ColitisUlcerative Colitis ChronicInflammatory Bowel Diseases+1 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT04844606

Observational

Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel Disease

The bidirectional effects between psychological distress and inflammatory bowel disease (IBD) activity mean that not only does increased IBD activity trigger p…

Crohn's DiseaseUlcerative ColitisInflammatory Bowel Diseases

Estimated

~$10 – $6,250

Montefiore Medical CenterNCT06510296

Phase 4

An Open-Label, Phase 4 Study to Evaluate the Efficacy and Safety of Dual Targeted Therapy With Vedolizumab Intravenous (IV) and Adalimumab Subcutaneous (SC) or Vedolizumab IV and Ustekinumab IV/SC in Moderate to Severe Crohn's Disease (CD)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together w…

Group-based Virtual Psychotherapy Intervention for Anxiety and Depression in Patients With Inflammatory Bowel Disease

This study is being done to better understand the complex relationship between mental health and Inflammatory Bowel Disease (IBD), with a particular focus on s…

Crohn's Disease (CD)Ulcerative Colitis (UC)Inflammatory Bowel Diseases (IBD)+2 more

Estimated

~$10 – $6,250

University of ChicagoNCT07796568

Phase 1

An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn's Disease, Ulcerative Colitis, and Chronic Granulomatous Disease Colitis Patients and Maintenance Therapy With Ustekinumab

Background: Crohn s disease (CD) is an inflammatory bowel disease. It causes inflammation of the gut. Symptoms may include diarrhea, abdominal pain, fatigue, …

Crohn's Disease

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT03167437

Observational

Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal Crohn's Disease: A Phase II Randomized Trial

This is a Phase II, single-center (Cleveland Clinic), two-arm, randomized, parallel-group superiority trial. The two arms will compare IOUS-guided margin selec…

Crohn's Disease (CD)

Estimated

~$10 – $6,250

The Cleveland ClinicNCT07680283

Observational

Randomized Controlled Trial of Online Pain Education Programs for Inflammatory Bowel Disease

Through a pilot randomized controlled trial (RCT), we aim to test the feasibility and preliminary impact of two online pain educations programs among adult pat…

Crohn's DiseaseUlcerative Colitis (UC)Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)

Estimated

~$10 – $6,250

Cedars-Sinai Medical CenterNCT07671313

Phase 4

MIRICURE: Mirikizumab With Curettage and Repair (Closure) for Perianal Fistulizing Crohn's Disease

This Phase 4, single-arm, open-label study will evaluate the effectiveness and safety of mirikizumab combined with surgical curettage and closure in adults wit…

Crohn's DiseasePerianal Fistula

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07782021

Phase 3

A Phase 3, Multicenter, Randomized Clinical Study to Evaluate Mirikizumab in Pediatric Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizu…

Crohn's Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT05509777

Infection Outcomes Among Advanced Therapy-naive Older Adult US Patients With UC/CD Initiating ENTYVIO, TNF-alpha Inhibitors, or Ustekinumab: A Retrospective Observational Matched-Cohort Study Using Medicare Claims Data, 2016-2025

More older people (more than 65 years of age) around the world are getting Ulcerative Colitis (UC) or Crohn's Disease (CD). This is happening because people ar…

Ulcerative ColitisCrohn's Disease

Estimated

~$10 – $1,125

TakedaNCT07250815