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152 recruiting studies matching your filters

A Medical Nutrition Supplement for Cystic Fibrosis

The goal of this study is to learn if one nutrition supplement formula works better than a different formula in adults with cystic fibrosis. The main question …

Cystic Fibrosis (CF)

Estimated

~$10 – $6,250

Ohio State UniversityNCT07163078

Phase 2

Endoscopic Ultrasound-Guided Chemoablation of Pancreatic Cysts - An Efficacy Trial

This phase II trial tests the effect of endoscopic ultrasound (EUS)-guided chemoablation in treating patients with pancreatic cysts. Pancreatic cancer is a fat…

Pancreatic Cystic Neoplasm

Estimated

~$10 – $6,250

Ohio State University Comprehensive Cancer CenterNCT07529483

Phase 1

A Pilot Study of Chemoprevention With Tamoxifen in Patients With Pre-Invasive Pancreas Mucinous Cystic Neoplasms Who Will Not Undergo Immediate Resection

Pancreatic mucinous cystic neoplasm (MCN) is a precursor to invasive pancreatic adenocarcinoma which occurs almost exclusively in females in their 5th-7th deca…

Pancreatic CystPancreatic Mucinous Cystic Neoplasm

Estimated

~$10 – $6,250

University of NebraskaNCT06320990

Phase 4

Ensuring Access to Optimal Therapy in Cystic Fibrosis: The ENACT Study

This clinical trial is examining the action and effects of several new drugs in the treatment of cystic fibrosis in children. In addition, several genetic fact…

Cystic Fibrosis (CF)

Estimated

~$10 – $6,250

Arkansas Children's Hospital Research InstituteNCT07148739

Rare CFTR Mutation Cell Collection Protocol (RARE)

Over 1,900 mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein are implicated in causing Cystic Fibrosis (CF). Pot…

Cystic Fibrosis

Estimated

~$10 – $1,125

George SolomonNCT03161808

Phase 2

A Phase 2a, Randomized, Placebo-Controlled, Double Blind Multiple Ascending Dose Study in Patients With Cystic Fibrosis Carrying the 3849 +10 Kb C->T Mutation to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84

The goal of this clinical trial is to learn if drug SPL84 is safe for adult patients with cystic fibrosis (CF). It will also learn if the drug works to treat w…

Cystic Fibrosis

Estimated

~$10 – $8,750

SpliSense Ltd.NCT06429176

Phase 4

Estrogen Supplementation and Bone Health in Women With CF (STURDY)

The goal of this study is to learn about the role of estrogen and other hormones in bone development in adolescent and young adult women with cystic fibrosis (…

Cystic FibrosisHypoestrogenism

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT05704036

Phase 2

Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study

Chronic constipation is common in children with cystic fibrosis (CF), likely due to impaired chloride channel function that reduces intestinal secretions. Stan…

Constipation Chronic IdiopathicCystic Fibrosis

Estimated

~$10 – $6,250

Children's Hospital Los AngelesNCT06413368

Phase 1

A Phase 1 Dose Escalation and Expansion Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 in Subjects With Advanced and/or Metastatic Solid Tumors Known to Express c-Kit

This open-label clinical trial will evaluate the safety and tolerability of NN3201 in subjects with advanced and/or metastatic solid tumors known to express c-…

Gastrointestinal Stromal TumorsSmall-cell Lung CancerAdenoid Cystic Carcinoma+4 more

Estimated

~$10 – $8,750

Novelty Nobility, Inc.NCT06805825

Observational

CGM Dynamic Index (CDI) for Predicting Prediabetes in People With Cystic Fibrosis

The primary objective of this pilot study is to develop a CGM-based model to predict the progression from prediabetes to diabetes in individuals with cystic fi…

PrediabetesCystic Fibrosis (CF)Cystic Fibrosis-related Diabetes

Estimated

~$10 – $6,250

Indiana UniversityNCT06642610

Phase 3

Sinonasal Therapies and Histologic Correlations for Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy

The investigators are doing this study to discover if it is appropriate for people with Cystic Fibrosis (CF) on highly effective modulator therapy (HEMT) to st…

Cystic Fibrosis (CF)Chronic Rhinosinusitis (CRS)

Estimated

~$10 – $6,250

Indiana UniversityNCT06996951

Observational

Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF)

Cystic fibrosis (CF) is a multisystem autosomal recessive inherited disease affecting approximately 75,000 individuals in USA. The sweat chloride (Cl) test rem…

Cystic Fibrosis

Estimated

~$10 – $6,250

Milton S. Hershey Medical CenterNCT05998629