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57 recruiting studies matching your filters

A Phase 2, Multicenter, Open-Label Study of Zolacabtagene Autoleucel (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Chronic Immune Thrombocytopenia (cITP) and Autoimmune Hemolytic Anemia (AIHA)

The purpose of this study is to evaluate the safety and efficacy of Zola-cel (BMS-986353), in participants with chronic immune thrombocytopenia (cITP) and auto…

Chronic Immune ThrombocytopeniaAutoimmune Hemolytic Anemia

Estimated

~$10 – $8,750

Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanyNCT07603557

Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (C…

Lung Cancer (Diagnosis)OsteochondromaSpitz Nevus+14 more

Estimated

~$10 – $1,125

Dana-Farber Cancer InstituteNCT07675967

Phase 3

A Multi-center, Open-label, Single-arm Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

This is a multinational, open label, single arm study that will evaluate the impact of early multi-immune modulation with rilzabrutinib in adult ITP patients w…

Immune Thrombocytopenia

A Phase II Prospective Study Evaluating Selective Depletion of CD45RA+ (Naïve) T Cells (TND) From Peripheral Blood Stem Cell (PBSC) Grafts for Prevention of Graft Versus Host Disease (GVHD) in Non-Malignant Diseases (NMDs)

This phase II trial investigates how well a naive T cell depleted graft work for the reduction of graft versus host disease in patients with non-malignant dise…

Bone Marrow FailureHemoglobinopathiesPrimary Immune Deficiency (PID)+4 more

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07660783

Phase 2

Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)

This is an open-label, phase 2 study for lower risk MDS and high risk CCUS patients who are transfusion independent. There will be two cohorts enrolled at the …

Clonal Cytopenia of Undetermined SignificanceMyelodysplastic Syndrome

Estimated

~$10 – $6,250

University of Colorado, DenverNCT07579429

Dual Antiplatelet Therapy (DAPT) in Patients With Baseline Thrombocytopenia

The use of clopidogrel as part of DAPT will be associated with lower bleeding rates compared to ticagrelor in patients with chronic thrombocytopenia requiring …

Baseline Thrombocytopenia

Estimated

~$10 – $750

Methodist Health SystemNCT06223607

Phase 2

AN INTERVENTIONAL PHASE 2, OPEN-LABEL, MULTI-CENTER STUDY TO EVALUATE SAFETY AND EFFICACY OF PF-06835375 IN ADULT PARTICIPANTS WITH MODERATE TO SEVERE PRIMARY IMMUNE THROMBOCYTOPENIA

This is a Phase 2, open-label, multicenter, multiple subcutaneous injection, safety and efficacy study of PF-06835375 in adult participants with primary immune…

Primary Immune Thrombocytopenia

Estimated

~$10 – $7,500

PfizerNCT05070845

Investigation of the Genetics of Hematologic Diseases

The purpose of this study is to collect and store samples and health information for current and future research to learn more about the causes and treatment o…

Bone Marrow Failure SyndromesErythrocyte DisorderLeukocyte Disorder+10 more

Estimated

~$10 – $750

St. Jude Children's Research HospitalNCT02720679

Phase 2

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

A phase II trial of a reduced intensity conditioned (RIC) allogeneic hematopoietic cell transplant (HCT) with post-transplant cyclophosphamide (PTCy) for idiop…

Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more

Estimated

~$10 – $6,250

Masonic Cancer Center, University of MinnesotaNCT06412497

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia Study-2

This is a prospective observational study designed to evaluate Immature Platelet Fraction or Immature Platelet Count and Platelet Function Analyzer-100/200 Clo…

Neonatal ThrombocytopeniaBleeding

Estimated

~$10 – $1,125

Karolinska InstitutetNCT04598750

Observational

Neonatal Platelet Transfusion Threshold Trial

The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion…

ThrombocytopeniaNeonatalPlatelet Transfusion+4 more

Estimated

~$10 – $7,500

NICHD Neonatal Research NetworkNCT06676904

Impact of Acute ITTP Therapies on Long Term Neurologic and Cognitive Outcomes in ITTP Survivors

1. We expect to find that the silent cerebral infarct (SCI) rate is two fold higher in patients treated without caplacizumab. We also expect to find that the r…

Immune Thrombotic Thrombocytopenia

Estimated

~$10 – $1,125

US Thrombotic Microangiopathy AllianceNCT06358703