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Impact of Timing of Initiation of Sulphonylurea Therapy on Neurodevelopmental Outcomes in Individuals With Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome Due to the V59M Mutation in the KCNJ11 Gene
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND …
Neurodevelopmental DisordersIntellectual DisabilityDevelopment Delay+3 more
Royal Devon and Exeter NHS Foundation TrustNCT05751525
A Prospective, Longitudinal and Observational Natural History Study for Children and Adults With Baker Gordon Syndrome - Genetic Autism Alliance
The goal of this study is to conduct a prospective, longitudinal assessment of the natural clinical progression of children and adults with Synaptotagmin1-Asso…
Rare DiseasesAutism or Autistic TraitsDevelopment Delay+4 more
University of Missouri-ColumbiaNCT06399952
Observational
A Center Based Early Intervention Program For Preschoolers With Developmental Disorders
The purpose of this study is to examine the effectiveness of a 12-week early intervention program that will include 12 weekly hours in an intensive center-base…
Development Disorder, ChildDevelopmental DisabilityDevelopment Delay+1 more
Stanford UniversityNCT04026386
Observational
Neural Prediction to Enhance Language Outcomes in Children With Cochlear Implant
The language outcome of children receiving cochlear implantation to address bilateral sensorineural hearing loss is more variable than that of typical hearing …
Bilateral Sensorineural Hearing LossSpeech and Language Development Delay Due to Hearing LossSocial Communication
Ann & Robert H Lurie Children's Hospital of ChicagoNCT05962359