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2,803 recruiting studies matching your filters

Understanding Stroke Outcomes: Stroke Resilience, Infarct Burden, and Long-Term Cognition

Background: Stroke is the fifth leading cause of death in the United States. It is also a leading cause of disability. More than 70% of people who survive str…

StrokeBrain DiseaseVascular Diseases+1 more

Estimated

~$10 – $675

National Institute of Neurological Disorders and Stroke (NINDS)NCT06615973

Observational

Deep Brain Stimulation Therapy in Movement Disorders

Background: \- In deep brain stimulation (DBS), a device called a neurostimulator is placed in the chest. It is attached to wires in parts of the brain that a…

Parkinson's Disease

Estimated

~$10 – $5,625

National Institute of Neurological Disorders and Stroke (NINDS)NCT02119611

Ultra-Short Echo Time 1H MRI in Individuals With Thoracic Musculoskeletal Disorders

In this research study we want to learn about new ways to use MRI (Magnetic Resonance Imaging) to take clearer pictures of the lungs. We will be using types of…

Muskuloskeletal DiseasesHealthyRespiratory

Estimated

~$10 – $1,125

Laura WalkupNCT07845708

Phase 3

A Study to Evaluate the Dose-exposure, Safety, and Exploratory Efficacy of Nerandomilast in Children and Adolescents From 2 Years to Less Than 18 Years of Age With Fibrosing Interstitial Lung Disease (Part A: Double-blind, Placebo-controlled in Children From 6 to Less Than 18 Years of Age and Open-label Active Treatment in Children From 2 to Less Than 6 Years of Age), Followed by an Open-label Phase With Active Treatment (Part B)

This study is open to children and adolescents aged 2 to 17 years with interstitial lung disease (ILD). Nerandomilast has just been approved in some countries …

Fibrosing Interstitial Lung Disease

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07366034

Phase 2

A Phase 2b, Randomized, Double Blind, Placebo Controlled, Parallel Group Trial to Assess the Efficacy and Safety of Obicetrapib in Participants With Preclinical Alzheimer's Disease (SPINOZA Trial)

A study evaluating Obicetrapib in adults potentially at risk for Preclinical Alzheimer's Disease

Preclinical Alzheimer's Disease

Estimated

~$10 – $8,750

NewAmsterdam PharmaNCT07794670

Observational

Adapting and Piloting a Stress Management Intervention to Reduce Cardiovascular Disease Risk Among Women Living With HIV

Women living with HIV have 2-4x higher risk for cardiovascular disease compared to women without HIV, with women living with HIV in the Southern US being parti…

StressBlood PressureCardiovascular Diseases (CVD)

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06811896

Phase 3

A Randomized, Double-blind, Placebo-controlled, 2-arm Multicenter Phase III Study to Assess the Efficacy and Safety of Ianalumab in Participants With Sjogren's Disease With High Symptom Burden (THALASSA)

The purpose of this study is to demonstrate the efficacy and safety of ianalumab (VAY736) 300 mg administered subcutaneously (s.c.) monthly for 52 weeks in adu…

Sjögren´s Disease

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT07621809

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Background: A person s genome is the collection of all their genes. A gene instructs individual cells to make proteins. Proteins are involved in all of our bo…

Human Immunodeficiency VirusCastleman's DiseaseKaposi's Sarcoma+1 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT03300830

Phase 2

A Phase 2 Randomized, Multicenter Study to Evaluate the Efficacy and Safety of Silevertinib, an Oral EGFR Inhibitor, in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma With Unmethylated MGMT Promoter and EGFRvIII

The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) b…

Glioblastoma (GBM)Newly Diagnosed GlioblastomaGBM+4 more

Estimated

~$10 – $8,750

Black Diamond Therapeutics, Inc.NCT07326566

Observational

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium

The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy infor…

Cardiovascular DiseasesMyocardial IschemiaHeart Diseases+4 more

Estimated

~$10 – $7,500

Fundación EPICNCT07286578

Phase 2

Effects of Treatments on the Microbiome in Healthy Volunteers and Patients With Atopic Dermatitis

Background: \- Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aureus bacteria. Researchers want to study…

EczemaDermatitisSkin Diseases, Genetic+2 more

Estimated

~$10 – $5,625

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT01631617

Phase 3

A Phase 3, Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-3)

The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an immediate rel…

Alzheimer DiseaseAgitation

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT06937229