Find your next paid study

The University of Texas Medical Branch, GalvestonNCT07758114

Degenerative Disc DiseaseDisc DegenerationLumbar Discogenic Pain

Randomized, Sham-Controlled, Multi-Center, Double-Blind Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft to Supplement Nucleus Pulposus Tissue in Participants With Lumbar Discogenic Pain Associated With Degenerative Disc Disease

VIA Disc NP is a non-surgical intervention intended to supplement nucleus pulposus tissue in degenerated intervertebral discs. This is a randomized, sham-cont…

VIVEX Biologics, Inc.NCT06778447

~$10 – $8,750

Dual Frequency, Dual Region Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease

Deep brain stimulation (DBS) in the dorsal region of the subthalamic nucleus (STN) is very effective for reducing motor symptoms of Parkinson's disease (PD). M…

Parkinson Disease

University of California, DavisNCT04650932

Phase 1

A Randomized, Double-blind, Placebo-controlled Single Ascending Dose and Open-label Multi-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ALN-APP in Adult Patients With Early-onset Alzheimer's Disease (EOAD)

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-A…

Early-Onset Alzheimer Disease

Alnylam PharmaceuticalsNCT05231785

~$10 – $8,750

Subgaleal Cortical Electrodes in Patients With Parkinson's Disease Undergoing Deep-brain Stimulation Therapy for Sensing and Adaptive Deep-brain Stimulation Over a 24-hour Period.

The purpose of this study is to test a new way to treat Parkinson's disease (PD). Subjects will be implanted with deep brain stimulator (DBS) devices and elect…

PD - Parkinson's Disease

University of California, San FranciscoNCT07398157

~$10 – $5,625

Losing Specificity: the Role of the Locus Coeruleus in Age-related Distractibility

A growing body of research has highlighted the importance of frontal regions, at both the functional and structural levels, in age-related declines in attentio…

AgingAlzheimer Disease

Virginia Polytechnic Institute and State UniversityNCT05574634

Phase 1

Single-tracer Multiparametric PET Imaging

The overarching goal of this project is to develop and evaluate a single-tracer multiparametric positron emission tomography (PET) imaging solution for simulta…

Healthy SubjectsCardiovascular Disease

University of California, DavisNCT06014515

Factors That Affect the Outcomes of Cardiothoracic and Vascular Surgery

Identify factors that contribute to perioperative morbidity and mortality in patients undergoing cardiac surgery that involves cardiopulmonary bypass. Identif…

Coronary Artery DiseaseValvular DiseasesVascular Diseases

University of California, DavisNCT01932411

~$10 – $750

Phase 4

Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD

Multi-site, randomized controlled trial to determine whether patients who report NO symptomatic benefit with their maintenance hand-held inhaler(s), benefit up…

COPD (Chronic Obstructive Pulmonary Disease)Chronic Obstructive Pulmonary Disease (COPD)

COPD FoundationNCT07816835

Partners Calciphylaxis Biobank and Patient Registry

Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles. There are significant ga…

CalciphylaxisCalcific Uremic ArteriolopathyEnd Stage Renal Disease+1 more

Massachusetts General HospitalNCT03032835

~$10 – $750

Congenital Heart DiseaseCongenital Heart Disease (CHD)

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

Starlight Cardiovascular, Inc. is sponsoring a prospective, multi-center, study to evaluate safety and effectiveness of the Lifeline Ductus Arteriosus Stent Sy…

Starlight Cardiovascular IncNCT07114718

~$10 – $8,750

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease

A Prospective, Multicenter, Randomized, Controlled Pivotal Trial to Evaluate the Safety and Effectiveness of Transcatheter Tricuspid Valve Repair With the Edwards PASCAL Transcatheter Valve Repair System and Optimal Medical Therapy (OMT) Compared to OMT Alone in Patients With Tricuspid Regurgitation

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Repair System in patients with symptomatic severe tricuspid regurgitation who hav…