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2,802 recruiting studies matching your filters

Role of Adiposomes in Diabetes-Associated Endothelial Dysfunction and Restorative Effects of Exercise and Metabolic Surgery

The development of type II diabetes (T2D) is strongly associated with obesity and both are well-established risk factors for cardiovascular disease. Knowing th…

ObesityDiabetesCardiovascular Diseases

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT05199454

Digital Measures for Clinical Trial Endpoints in Huntington's Disease (MEND-HD)

MEND-HD is a longitudinal study evaluating the feasibility of passive monitoring of gait and chorea in patients with HD and the meaningfulness of these outcome…

Huntington DiseaseHealthy

Estimated

~$10 – $750

University of RochesterNCT07010705

Phase 2

A Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Systemic Sclerosis

RESET-SSc: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T cell therapy, in Subjects with Systemic Sclerosis

Systemic SclerosisSclerodermaInterstitial Lung Diseases

Estimated

~$10 – $7,500

Cabaletta BioNCT06328777

Phase 1

An Investigator-initiated Clinical Trial of Safety and Efficacy of Transplantation of Human Induced Pluripotent Stem Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)

To evaluate the safety and efficacy of transplantation of human induced pluripotent stem cell-derived dopaminergic progenitors, CT1-DAP001, into the corpus str…

PD - Parkinson's Disease

Estimated

~$10 – $6,250

University of California, San DiegoNCT06482268

Phase 4

Quantitation of Hepatic Mitochondrial Fluxes in Humans With Nonalcoholic Fatty Liver Disease (NAFLD)

In this study the investigators will quantitate hepatic mitochondrial fluxes in T2D patients with NAFL and NASH before and after 16-weeks treatment with the in…

Non-Alcoholic Fatty Liver DiseaseType 2 DiabetesMitochondrial Metabolism Disorders

Estimated

~$10 – $6,250

The University of Texas Health Science Center at San AntonioNCT05305287

Phase 1

A Phase I Single-Center Open-label Study of C.001 in Patients With Significant Retinal Pigment Epithelium Mediated Maculopathy (RMM)

This is a first-in-human Phase 1 study evaluating the safety and tolerability of C.001 in patients with retinal diseases involving degeneration of the retinal …

Geographic AtrophyStargardt DiseaseRPE-mediated Maculopathy+1 more

Estimated

~$10 – $8,750

Cellio Therapeutics IncNCT07594236

Observational

Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE)

Heart valve disease and weakened heart muscle (left ventricular systolic dysfunction) are common in older adults and often go undetected until serious complica…

Valvular Heart Disease PatientsAortic StenosisMitral Regurgitation+1 more

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07756398

ATHN Transcends: A Natural History Cohort Study of the Safety, Effectiveness, and Practice of Treatment in People With Non-Neoplastic Hematologic Disorders

In parallel with the growth of ATHN's clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently F…

Hematologic DisorderBleeding DisorderConnective Tissue Disorder+10 more

Estimated

~$10 – $1,125

American Thrombosis and Hemostasis NetworkNCT04398628

Phase 1

A Phase 1, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

This is a Phase 1, multicenter, open-label study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of DNL952 in adult part…

Late-onset Pompe Disease

Estimated

~$10 – $8,750

Denali Therapeutics Inc.NCT07354724

Observational

Neuromodulation for the Treatment of Postural Instability in Patients With Parkinson's Disease

This study will compare different treatment schedules of combined transcranial direct current stimulation (tDCS) and transcranial ultrasound stimulation (TUS) …

Adults With Parkinson's Disease

Estimated

~$10 – $7,500

Felipe Fregni, MD, PhD, MPHNCT07767006

Observational

Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients

This pilot study will investigate the potential efficacy of VM100, a nutritional supplement specifically formulated for patients with DMD, on quality of life a…

Duchenne Muscular DystrophyDuchenne DiseaseMuscular Dystrophy in Children+2 more

Estimated

~$10 – $6,250

University of FloridaNCT07766980

Phase 3

A Multicenter Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Zigakibart in Adults With Primary IgA Nephropathy.

The purpose of this study is to determine if zigakibart is safe and effective for long-term use in patients with immunoglobulin A nephropathy (IgAN). This is a…

Kidney DiseasesKidney Diseases, ChronicUrological Diseases+5 more

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT06858319