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2,801 recruiting studies matching your filters

A Randomized, Double-Blind, Placebo-controlled, Single- and Multiple-ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, Pharmacodynamics and Clinical Activity of BBT002 in Healthy Volunteers and Patients With COPD or CRSwNP

Randomized study of single and multiple doses of BBT002 in healthy volunteers and in adult patients with chronic obstructive pulmonary disease (COPD) or chroni…

Chronic Obstructive Pulmonary Disease

Estimated

~$10 – $8,750

Bambusa TherapeuticsNCT06944925

Phase 2

An Open-Label, Exploratory, Phase 2 Scintigraphy Study Evaluating 18F-mFBG for Imaging Myocardial Sympathetic Innervation in Subjects With and Without Lewy Body Diseases

This is a Phase 2 study evaluating the positron-emitting radiopharmaceutical 18F-mFBG as an imaging agent for quantification of the effect of neurodegenerative…

Parkinson Disease (PD)Lewy Body Dementia (LBD)

Estimated

~$10 – $8,750

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)NCT07176286

Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement

The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full ede…

Edentulous MouthPeriodontal DiseasesPeriodontitis, Adult+1 more

Estimated

~$10 – $750

Case Western Reserve UniversityNCT06149585

Phase 2

Study of TCR Alpha Beta T-Cell and CD19 B-Cell Depletion for Hematopoietic Cell Transplantation From Haploidentical Donors in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children

This research is being done to learn if a new type of haploidentical transplantation using TCR alpha beta and CD19 depleted stem cell graft from the donor is s…

Primary Immune Deficiency DisordersMetabolic Disease

Estimated

~$10 – $6,250

Johns Hopkins All Children's HospitalNCT04414046

Phase 1

A Phase I-II Study of High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Abatacept for the Prevention of Graft-versus-Host Disease (GvHD) Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Phase I-II studying post transplant cyclophosphamide, bortezomib and sitagliptin for GvHD prevention in allogeneic HSCT. Adults with hematologic malignancies u…

GVHD - Graft-Versus-Host Disease

Estimated

~$10 – $7,500

Northwell HealthNCT07675174

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Psychosis Associated With Alzheimer's Disease

The purpose of this study is to evaluate KarXT + KarX-EC as a treatment for psychosis associated with Alzheimer's disease.

Alzheimer DiseasePsychosis

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT06947941

Observational

Validation of cueStim for Reduction of Freezing of Gait in Parkinson's Disease

The goal of this clinical trial is to learn if the cueStim device can reduce the duration of freezing of gait (FoG) that occurs in patients with Parkinson's Di…

Parkinson's Disease With Freezing of Gait

Estimated

~$10 – $8,750

Fortis Medical Devices LimitedNCT07675408

Observational

A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients

The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their…

Disorders of Gut-brain InteractionInflammatory Bowel Disease (IBD)Irritable Bowel Syndrome+2 more

Estimated

~$10 – $6,250

Stanford UniversityNCT07676136

Phase 2

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase II Clinical Study to Evaluate the Efficacy and Safety of H021 Enteric-coated Tablets in Patients With Moderately to Severely Active Crohn's Disease (CD)

This study employs a multicenter, randomized, double-blind, placebo-controlled, parallel-group, continuous treatment design to evaluate the efficacy, safety, P…

Crohn's Disease

Estimated

~$10 – $8,750

Jiangsu Carephar Pharmaceutical Co., Ltd.NCT07677514

Rett Syndrome Real World Data Observational Registry

The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with t…

Rett SyndromeRett Syndrome, AtypicalGenetic Disease+7 more

Estimated

~$10 – $750

International Rett Syndrome FoundationNCT05432349

Phase 1

A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-002 in Participants With Von Willebrand Disease (Velora Pioneer)

This is a first-in-human (FIH), Phase 1/2, 3-part open-label, dose escalation, safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and efficacy s…

Von Willebrand Disease (VWD)Von Willebrand Disease (VWD), Type 1Von Willebrand Disease (VWD), Type 2+1 more

A Randomized, Investigator-Masked, Single-Center Study Evaluating Tolerability, Symptomatic Improvement, and Visual Functional Outcomes With the Use of Over-the-Counter Lubricating Eye Drops in Subjects With Dry Eye Disease

A study to evaluate the effect of over- the- counter (OTC) lubricating eye drops on tolerability, symptoms and visual outcomes in patients with dry eye disease…

Dry Eye Disease (DED)

Estimated

~$10 – $7,500

Andover Research Eye InstituteNCT07676084