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2,202 recruiting studies matching your filters

A Phase 2 Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer

The goal of this clinical trial is to learn if adding amplitude-modulated radiofrequency electromagnetic fields (AM RF EMF) to Fruquintinib in metastatic color…

Metastatic Colorectal Adenocarcinoma

Estimated

~$10 – $7,500

Barbara Ann Karmanos Cancer InstituteNCT07130903

A Prospective, International, Multicenter Registry of Patients Undergoing Segmental Mandibular Defects Reconstruction (SMDR) After Mandibular Resection for Tumors and Drugs-induced Osteonecrosis

Prospective will be collected in a minimum of 300 patients presenting with an acquired segmental mandibular defect ≥ 2 cm secondary to OSSC removal and drugs-i…

Mandibular ReconstructionSegmental Mandibular Defects

Estimated

~$10 – $1,125

AO Innovation Translation CenterNCT04098146

Phase 1

A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the max…

Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more

Alanyl-glutamine Supplementation of Standard Treatment for C. Difficile Infection: a Randomized, Double-blind, Placebo-controlled Trial

This is a randomized, double-blind, placebo-controlled trial to determine the optimal dose and safety of oral alanyl-glutamine between 4, 24, and 44 g doses ad…

Clostridioides Difficile InfectionClostridium Difficile InfectionClostridium Difficile Diarrhea+1 more

Estimated

~$10 – $6,250

University of VirginiaNCT04305769

Phase 4

PREoperative Targeted OnabotulinumtoXina Injection for Abdominal Wall Reconstruction: A Randomized, Double-Blind, Placebo-Controlled Trial

This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection o…

Hernia Abdominal WallBotox InjectionHernia Incisional Ventral+4 more

Estimated

~$10 – $6,250

The Cleveland ClinicNCT07220382

Phase 3

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

The goal of this clinical trial is to learn if reducing bacterial load on the skin and nostrils with topical antibacterial soap and ointment, respectively, red…

Surgical Wound Infection

Estimated

~$10 – $6,250

The Cooper Health SystemNCT07142408

Phase 2

A Prospective, Pre-Hospital Comparison of Normal Saline Versus Half-Normal Saline, After Universal Calcium Chloride Administration, to Improve Outcomes in Pulseless Electrical Activity Patients

The Carilion Clinic and Virginia Tech Carilion School of Medicine, in conjunction with Roanoke Fire-EMS, Botetourt County Department of Fire \& EMS and Salem F…

Cardiac ArrestPulseless Electrical Activity

Estimated

~$10 – $7,500

Carol BernierNCT05283850

Observational

Examining the Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV (HEALTH-Cog)

People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such r…

HIV InfectionsCognitive Impairment

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06013579

Phase 1

A Phase 1a, Dose Escalation, Safety and Tolerability Study of NX-1607, a Casitas B-lineage Lymphoma Proto-oncogene (CBL-B) Inhibitor, in Adults With Advanced Malignancies, With Phase 1b Expansion in Select Tumor Types

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-1607 in patients wit…

Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more

Estimated

~$10 – $8,750

Nurix Therapeutics, Inc.

Neurogenetic Disorders: A Longitudinal Study on Natural History and Intervention Strategies

The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medi…

Neurodevelopmental DisordersIntellectual DisabilityDevelopmental Delay+4 more

Estimated

~$10 – $750

Columbia UniversityNCT03492060

Observational

Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents

The present study is an open trial of ketogenic diets for adolescents and young adults (ages 12-21 yrs) in the depressive or mixed phases of bipolar disorder (…

Bipolar Disorder (BD)Bipolar Disorder NOSBipolar Disorder I or II+2 more

Estimated

~$10 – $6,250

University of California, Los AngelesNCT06920940

Phase 3

Robotic-Assisted Laparoscopic Prostatectomy (RALP) and SAFE (Saline Assisted Fascial Engorgement) Nerve Preservation Guided by Micro-ultrasound: A Phase III RCT

Robotic-assisted radical prostatectomy (RALP) has become the standard of care in the management of localized prostate cancer. However, post-prostatectomy erect…

Prostate CancerErectile Dysfunction

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT06945315