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2,199 recruiting studies matching your filters

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women (OvAR-Y): an In-Silico Feasibility Trial

Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic r…

Uterine CancerRectal CancerColon Cancer+9 more

Estimated

~$10 – $750

Washington University School of MedicineNCT06904365

Phase 1

A Phase I Clinical Trial of Ivonescimab and ADG126, Alone, and in Combination With 5-FU/LV or FOLFIRI in MSS Advanced/Metastatic Colorectal Cancer

This phase I trial studies the safety, side effects, and best dose of ADG126, in combination with ivonescimab alone, in combination with ivonescimab, leucovori…

Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+1 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT07363408

Phase 1

A Phase I First-in-human Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Antiviral Activity of the Broadly Neutralizing Antibody BNT351 in Adults Living Without and With HIV

This study will test the safety and blood levels of the antibody BNT351 in people living without and with human immunodeficiency virus (HIV). This study will a…

HIV -1 Infection

Estimated

~$10 – $7,500

BioNTech SENCT07392372

UCSF Center for Genome Surgery Biobank and Registry

Gene editing approaches (including but not limited to: CRISPR, LNP, AAV, RNAi etc.) for the medical specialty of interventional genomics require (1) determinat…

Any Conditions That Are Genetic or Suspected to be Genetic in Origin

Estimated

~$10 – $675

University of California, San FranciscoNCT07396285

Phase 2

Randomized Controlled Trial of Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism

The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression…

Autism Spectrum DisorderChallenging BehaviourAggression+2 more

Estimated

~$10 – $7,500

Jeremy Veenstra-vanderweeleNCT07091279

Phase 2

A Global, Multicenter, Randomized, Dose-Optimization Phase II Study of Trastuzumab Rezetecan (SHR-A1811) in Combination With mFOLFOX6 (-1) and Bevacizumab as First-Line Treatment in Patients With HER2-Positive Advanced Colorectal Cancer (HORIZON-CRC221)

This global study is being conducted to evaluate the safety and determine the recommended phase 3 dose of trastuzumab rezetecan in combination with mFOLFOX6 ch…

Advanced Colorectal Cancer Expressing HER2

Estimated

~$10 – $8,750

Jiangsu HengRui Medicine Co., Ltd.NCT07796763

Observational

Pilot Clinical Study Evaluating Endoscopic Sleeve Gastroplasty (ESG) for Obese Patients With Heart Failure With Preserved Ejection Fraction

This is a small research study to see whether losing weight with a minimally invasive weight-loss procedure called endoscopic sleeve gastroplasty (ESG) can hel…

Obesity (BMI>30)Heart Failure With Preserved Ejection Fraction (HFPEF)

Estimated

~$10 – $6,250

Cedars-Sinai Medical CenterNCT07798219

Observational

A Prospective, Multicenter, Single-arm, Post Market Study to Evaluate the Safety and Performance of the Signia™ Circular Stapler With Tri-Staple™ Technology in Elective Open or Minimally Invasive Left-sided Colon, Sigmoid, and Rectal Resections (SECURE)

The purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular…

Colorectal AnastomosisLeft-sided Colon ResectionAnastomotic Leak+8 more

Estimated

~$10 – $7,500

Medtronic - MITGNCT07351071

Phase 1

A Randomized, Placebo-Controlled, Double-Blind, Proof-of-Concept Study of ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)

This is a 2-part study evaluating ATV-1601 in participants with moderate to severe HHT. Part 1 is a randomized, double-blind, placebo-controlled study evaluati…

Hereditary Hemorrhagic Telangiectasia (HHT)Osler Weber Rendu Disease

Estimated

~$10 – $8,750

Atavistik Bio, IncNCT07601425

Phase 2

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients with Refractory Advanced/Metastatic Microsatellite Stable Colore…

Colorectal Cancer

Estimated

~$10 – $8,750

Criterium, Inc.NCT06992258

Abbott Structural Heart Device Registry

The Abbott Structural Heart (SH) Registry is being conducted to confirm the safety and performance of Abbott's SH devices in a post-market, real-world setting.…

Heart DiseasesASD - Atrial Septal DefectVSD - Muscular Ventricular Septal Defect+3 more

Estimated

~$10 – $1,125

Abbott Medical DevicesNCT06590467

Observational

A Pilot Trial to Evaluate the Effectiveness of Navigation, Interactive Web Education, or the Combination of Both to Promote Guideline-Concordant Colorectal Cancer Surveillance Care

This pilot clinical trial looks at whether patient navigation services, an interactive web education intervention, called Current Together After Cancer (CTAC),…

Stage I Colorectal Cancer AJCC v8Stage II Colorectal Cancer AJCC v8Stage III Colorectal Cancer AJCC v8

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT06995924