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Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction: I-I-CAPTAIN-HF

An increasing number of guideline-directed medical therapies (GDMT) have been developed for patients with chronic heart failure with reduced ejection fraction …

Heart Failure With Reduced Ejection Fraction

Estimated

~$10 – $6,250

University of Colorado, DenverNCT06526988

Phase 1

A Randomized Clinical Trial to Assess Safety and Efficacy of Allogeneic Adipose-derived Mesenchymal Stem Cells in Promoting the Recovery of Erectile Function Post Radical Retropubic Prostatectomy of Localized Prostate Cancer

This is a phase 1/2 single center, pilot study to assess safety and efficacy of allogeneic adipose-derived mesenchymal stem cells (HB-adMSCs) and to evaluate t…

Erectile DysfunctionProstate Cancer

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT07048314

Phase 4

Neural Mechanisms of Anticholinergic Burden in Mid- to Late-Life Schizophrenia Spectrum

In this study, the investigators will examine whether a deprescription of unnecessary anticholinergic drugs (benztropine or trihexyphenidyl) can augment qualit…

SchizophreniaSchizoaffective Disorder

Estimated

~$10 – $7,500

Deepak K. Sarpal, M.D.NCT06562608

Phase 1

Axicabtagene Ciloleucel in Relapsed or Refractory HIV-Associated Aggressive B-Cell Non-Hodgkin Lymphoma

This phase I trial evaluates the side effects and usefulness of axicabtagene clioleucel (a CAR-T therapy) and find out what effect, if any, it has on treating …

Estimated

~$10 – $7,500

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection Registry Study

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal …

Liver Transplant SurgeryColorectal Cancer MetastaticColon Cancer Liver Metastases

Estimated

~$10 – $750

Northwestern UniversityNCT06698146

Phase 4

Optimization of Beta-lactam Dosing in Critically Ill Patients With Suspected or Documented Antimicrobial Resistant Gram-Negative Infections With Cystatin-C (OPTIMIZE-GNI)

This is a Phase 4, interventional, multi-center pharmacokinetics (PK) study in up to 200 adult patients who are residing in an ICU. This study will compare the…

Bacterial Infection

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT06709521

Phase 2

A Phase 2, Open-label, Multicenter Study to Evaluate Efficacy and Safety of Zanidatamab for the Treatment of Participants With Previously Treated HER2-expressing Solid Tumors (DiscovHER PAN-206)

The purpose of this study is to evaluate the efficacy and safety of zanidatamab for the treatment of participants with previously treated solid tumors that hav…

Breast CancerGastric CancerEsophageal Cancer+9 more

Estimated

~$10 – $8,750

Jazz PharmaceuticalsNCT06695845

Registry of Patients Undergoing Endoscopic Ultrasound (EUS) Procedures Using the RIVOS™ EUS Access Device

This is a prospective study of patients undergoing EUS procedures using the RIVOS™ EUS access device.

Pancreatic Fluid CollectionsBiliary ObstructionPancreatic Duct Obstruction+2 more

Estimated

~$10 – $1,050

Orlando Health, Inc.NCT07696572

Phase 2

A Phase 2, Randomized, Open-Label Study Comparing Telisotuzumab Adizutecan (ABBV-400) Monotherapy to the Current Standard of Care in Subjects With Post Adjuvant ctDNA Positive Colorectal Cancer and No Radiographic Evidence of Disease (NED)

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess change in disease activity when tel…

Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization

The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) …

Colorectal Cancer

Estimated

~$10 – $6,250

University of Colorado, DenverNCT07569250

Observational

Navigating the Transition to Adulthood: A Dual Language Mobile App for Latino Youth With ASD and Their Families

The purpose of this study is to determine useability and satisfaction characteristics,product usage data,methodological feasibility parameters and feasibility …

Autism Spectrum Disorder (ASD)

Estimated

~$10 – $6,250

The University of Texas Health Science Center, HoustonNCT07170163

Clinical Investigation to Demonstrate Performance, Safety and Clinical Benefits of the Persona Revision Knee System

The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision tot…

Arthroplasty ComplicationsInfectionKnee Disease+1 more

Estimated

~$10 – $1,125

Zimmer BiometNCT04821154