Find your next paid study

Merck Sharp & Dohme LLCNCT04375800

~$10 – $8,750

Phase 1

A Phase 1/2 Open-label Intrathecal Administration of MELPIDA to Determine Its Safety and Efficacy for Patients With Spastic Paraplegia Type 50 (SPG50) Caused by Mutation in the AP4M1 Gene.

MELPIDA is proposed for the treatment of subjects with SPG50 and targets neuronal cells to deliver a fully functional human AP4M1 cDNA copy via intrathecal inj…

Spasticity, MuscleMicrocephalyIntellectual Deficiency+3 more

Elpida Therapeutics SPCNCT05518188

~$10 – $8,750

Observational

Pivotal, Prospective, Randomized, Controlled, Multicenter Clinical Trial of BioPoly® Partial Resurfacing Knee Implant for Treatment of Focal Cartilage Lesions of the Distal Femur

The goal of this randomized controlled clinical trial is to demonstrate the safety and effectiveness of the BioPoly® Partial Resurfacing Knee Implant for the t…

Knee Pain ChronicKnee OsteoarthritisCartilage Damage+3 more

Gynecologic CancerProstate CancerLung Cancer+1 more

~$10 – $8,750

BioPoly LLCNCT06915363

Observational

Implement and Evaluate the CARE Tool in a Randomized Trial

This study is a multi-site randomized trial to study the implementation of the CARE Tool and evaluate the CARE Tool. The CARE Tool is a web-based tool that giv…

Washington University School of MedicineNCT07296887

A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer

Gastrointestinal (GI) cancers remain a major global health burden, largely due to the lack of effective and accessible early screening strategies. Current diag…

Hepatocellular Carcinoma (HCC)CholangiocarcinomaPancreatic Ductal Adenocarcinoma (PDAC)+3 more

City of Hope Medical CenterNCT07224750

Phase 4

A Single Arm Phase 4 Trial to Evaluate the Safety and Efficacy of Oral Fruquintinib in the Treatment of Refractory Metastatic Colorectal Cancer in Patients From Minority Populations Underrepresented in Prior Fruquintinib Studies

High blood pressure (hypertension) is a known side effect of the treatment with fruquintinib. Current research does not provide a clear answer whether minority…

Splicing-Based Predictive Learning for Individual Chemotherapy Evaluation in Colorectal Cancer (SPLICE)

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Although adjuvant chemotherapy improves survival after curativ…

Colorectal CancerColorectal Cancer RecurrentColorectal Cancer Stage II+1 more

City of Hope Medical CenterNCT07226115

Predicting Recurrence-Free Survival in Stage III and High-Risk Stage II Colorectal Cancer After Curative-Intent Treatment

This study will develop an assay to predict disease recurrence in patients with stage II/III CRC after receiving adjuvant chemotherapy, using genome-wide DNA m…

Colorectal CancerColorectal AdenocarcinomaColorectal Cancer Stage II+2 more

City of Hope Medical CenterNCT06314958

Observational

Optimizing Evidence-Based Interventions to Improve Colorectal Cancer Screening Adherence in Community Health Clinics

This is a 4 arm pragmatic trial to test a multicomponent intervention designed to improve adherence to colorectal cancer screening.

Colo-rectal Cancer

Yale UniversityNCT07345676

Development of a cfDNA 5mC/5hmC-based Epigenetic Biomarker Panel to Predict Chemotherapy Efficacy in Metastatic Colorectal Cancer

The EpiCORE study aims to identify cfDNA-based epigenetic markers predictive of response to first-line chemotherapy (FOLFOX or FOLFIRI) in metastatic colorecta…

CRC (Colorectal Cancer)

City of Hope Medical CenterNCT07224815

Phase 4

Iron Needed for Function and Undesirable Symptoms in Elderly With Heart Failure With Preserved Ejection Fraction

This randomized, double-blind, placebo-controlled clinical trial evaluates intravenous ferric derisomaltose in older adults with HFpEF and iron deficiency.

Heart Failure With Preserved Ejection FractionIron Deficiency

Duke UniversityNCT07686692

Phase 3

A Randomized Controlled Trial of Methylprednisolone Versus Standard of Care in Patients Undergoing Major Hepatectomy

The purpose of this study is to test whether receiving methylprednisolone before surgery will reduce the side effects of having surgery, such as infections and…

Hepatectomy