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56 recruiting studies matching your filters

Neurophysiological Effect of Ketamine in Patients With Severe Traumatic Brain Injury

Traumatic brain injury (TBI) accounts for approximately 2.5 million visits to emergency departments in the United States each year. After decades of research, …

Traumatic Brain InjuryTraumatic Encephalopathy

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT06062628

Harnessing the Power of Technology to Transform Delirium Severity Measurement in the ICU

The goal of this observational study is to develop a passive digital marker (PDM) for delirium severity and examine its performance in comparison to validated …

Intensive Care Unit DeliriumEncephalopathyDelirium

Estimated

~$10 – $750

Mayo ClinicNCT06172491

Observational

Endoscopic Ultrasound Embolization of Porto-Systemic Shunt for Management of Medically Refractory Hepatic Encephalopathy: A Randomized Trial

The goal of this clinical trial is to learn if endoscopic ultrasound guided (EUS guided) spontaneous porto-systemic shunt (SPSS) embolization works to treat re…

Hepatic EncephalopathyLiver CirrhosisPortal Shunt Systemic

Estimated

~$10 – $6,250

Rutgers, The State University of New JerseyNCT07553858

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in th…

HIETBI (Traumatic Brain Injury)TBI+2 more

Estimated

~$10 – $750

Children's Hospital Los AngelesNCT06195345

The International Registry for Leigh Syndrome

The purpose of this study is to develop a database containing clinical and laboratory information for patients with Leigh syndrome. The goal is to provide a gr…

Leigh SyndromeLeigh DiseaseLeigh's Necrotizing Encephalopathy+2 more

Estimated

~$10 – $750

The University of Texas Health Science Center, HoustonNCT03137355

Assessing Patient Engagement and Understanding in Hepatic Encephalopathy Clinical Research

This study aims to investigate the influences behind patient choices regarding involvement, discontinuation, or re-engagement in hepatic encephalopathy clinica…

Hepatic Encephalopathy

Estimated

~$10 – $1,050

Power Life Sciences Inc.NCT06201988

The Rare Disease Clinical Research Network Natural History Study of MNGIE

This is a multi-center natural history study of Mitochondrial NeurogastroIntestinal Encephalopathy (MNGIE). Patients will be followed over time to assess clini…

Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)

Estimated

~$10 – $750

Columbia UniversityNCT01694953

Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, …

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more

Phase 2

A Phase 2, Two-Stage, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia With Long-Term Follow-Up

Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 6…

Hypoxic-Ischemic Encephalopathy

Estimated

~$10 – $8,750

ReAlta Life Sciences, Inc.NCT05778188

Research Registry for Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL)

This study is being done in order to create a registry (list) of people interested in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Le…

Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and Leukoencephalopathy

Estimated

~$10 – $750

University of Wisconsin, MadisonNCT05567744

Functional and Neurodevelopmental Outcomes Following Intensive Multimodal Neurorehabilitation in Pediatric Patients With Neurodevelopmental Disorders, Including Chromosomal Abnormalities

This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitati…

Neurodevelopmental DisordersNeurodevelopmental Disorders (NDD)Neurodevelopmental Disorders and Developmental Abnormalities+20 more

Estimated

~$10 – $1,125

Genetics of Epilepsy and Related Disorders

Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to epilepsy and rela…

EpilepsyEpileptic Encephalopathy

Estimated

~$10 – $750

Boston Children's HospitalNCT01858285