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555 recruiting studies matching your filters

A Phase 1, Multicenter, Open-Label Study of BMS-986553, CD19 In Vivo Chimeric Antigen Receptor (CAR) T Cells, in Participants With Refractory Autoimmune Diseases

The purpose of this study is to evaluate the safety and tolerability of BMS-986553, CD19 in vivo Chimeric Antigen Receptor (CAR) T cells, in participants with …

Systemic Lupus ErythematosusSjögren's DiseaseRheumatoid Arthritis+3 more

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07873931

Phase 3

An Open-Label, Multicenter Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

The main goal of the study is to find out whether XEMBIFY, given once a week under the skin, provides similar levels of immunoglobulin G in the blood over time…

CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy)

Estimated

~$10 – $8,750

Grifols Therapeutics LLCNCT07540221

Phase 1

A Double-Blinded, Randomized Influenza Virus Challenge Trial of Recombinant Influenza RG-A/Arkansas/08/2020 (pH1N1) in Healthy Adults to Assess Safety and Optimal Infectious Dose

This protocol describes a clinical trial to develop and validate a Controlled Human Infection Model (CHIM) for influenza A/Arkansas/08/2020 (pH1N1). The study …

Influenza

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT07110532

Phase 3

A Phase 3 Randomized, Observer-Blind, Controlled Study to Evaluate the Immunogenicity, Reactogenicity and Safety of an mRNA-based Seasonal Influenza Vaccine, in Adults 18-64 Years of Age

This clinical trial will study an investigational seasonal influenza vaccine in adults 18 to 64 years of age. The vaccine is based on messenger ribonucleic aci…

Influenza, Human

Estimated

~$10 – $7,500

GlaxoSmithKlineNCT07851246

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (mult…

Acute Myeloid Leukaemia (AML)Follicular Lymphoma ( FL)

TRUDI: A Phase II Study of Neoadjuvant Trastuzumab Deruxtecan and Durvalumab for Stage III, HER2-expressing Inflammatory Breast Cancer

The purpose of this study is to test the safety and effectiveness of an investigational drug combination (trastuzumab deruxtecan and durvalumab) to learn wheth…

Invasive Breast CancerInflammatory Breast Cancer Stage IIIHER2-positive Breast Cancer+2 more

Estimated

~$10 – $7,500

Filipa Lynce, MDNCT05795101

Phase 1

A Phase 1 Clinical Trial Evaluating the Safety and Tolerability of Bilateral Hemispheric 5-ALA-Mediated Sonodynamic Therapy Using the LIDU System Before Standard Radiochemotherapy and During Adjuvant Temozolomide in Patients With Histologically Proven Newly Diagnosed Butterfly Glioma

This study is assessing the safety and tolerability of 5-ALA- mediated Porphyrin Metabolite Activation (PoMA) with LIDU ultrasound, in patients who have just b…

Glioblastom WHO Grade 4GBMbGBM+3 more

Estimated

~$10 – $8,750

Alpheus Medical, Inc.NCT07862647

Observational

The Effects of Morning Light Therapy on IBD Activity and Symptoms

The pilot study will focus on the effects of morning light therapy (MLT) in adult patients with ulcerative colitis (UC) who have evidence of poor sleep quality…

Inflammatory Bowel Disease

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07207200

Phase 1

A Phase 1, Randomized, Controlled, Dose-Ranging Study to Evaluate the Safety and Immunogenicity of Influenza A Group 1 and Influenza A Group 2 mRNA Chimeric Hemagglutinin Vaccine Candidates Alone and in Combination in Healthy Adults.

This is a Phase 1, randomized, controlled, dose-ranging clinical trial to assess the safety and immunogenicity of novel influenza A Group 1 and influenza A Gro…

Influenza

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT07703514

Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)

Background: Loss of the sense of smell can seriously affect a person's quality of life. The ability to smell can be damaged by many factors, including illness…

Respiratory Tract InfectionSmell DisorderInfluenza+7 more

Estimated

~$10 – $675

National Institute on Deafness and Other Communication Disorders (NIDCD)NCT07149428

Phase 3

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of DNTH103 In Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

The purpose of this Phase 3 study is to demonstrate the efficacy of claseprubart (DNTH103) as compared to placebo in participants with chronic inflammatory dem…

Chronic Inflammatory Demyelinating Polyneuropathy

Estimated

~$10 – $8,750

Dianthus TherapeuticsNCT06858579

Real World Study of Efficacy and Adherence to Subcutaneous vs. Intravenous Vedolizumab in Patients With Inflammatory Bowel Disease Using a Novel Remote MONITORing Intervention (MONITOR Study)

The goal of this observational study is to assess the feasibility and effectiveness of a remote monitoring digital health system on adherence, clinical outcome…

Inflammatory Bowel Disease (IBD)Crohn's DiseaseUlcerative Colitis

Estimated

~$10 – $750

Mercy Medical CenterNCT06750731