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6 recruiting studies matching your filters

Platform Trial for Salvage Consolidation Therapy in Dimorphic Fungi

This Phase II platform trial will evaluate the safety, tolerability, and effectiveness of investigational antifungal agents as salvage or consolidation therapy…

CoccidioidomycosisBlastomycosisHistoplasmosis+2 more

Estimated

~$10 – $6,250

University of MinnesotaNCT07804368

Studies of Disorders With Increased Susceptibility to Fungal Infections

Background: \- Researchers are interested in studying disorders that make individuals more susceptible to fungal infections, specifically infections with the …

Fungal InfectionsPrimary Immune Deficiencies

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT01222741

Phase 4

Itraconazole Therapy In Bronchiectasis With Airway Mold: A Single-Arm Pilot Trial Of Feasibility, Safety, And Impact On Respiratory Symptoms And Airway Microbiome Diversity

The primary objective of this study is to evaluate the feasibility of itraconazole therapy in patients with bronchiectasis and airway mold. Feasibility will be…

BronchiectasisFungal Infection of Upper Respiratory Tract

Estimated

~$10 – $6,250

Mayo ClinicNCT07283497

Phase 2

A Phase 2, Open-Label, Single-Arm, Sequential-Panel Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Posaconazole (POS, MK-5592) Intravenous and Powder for Oral Suspension Formulations in Pediatric Participants From Birth to Less Than 2 Years of Age With Possible, Probable, or Proven Invasive Fungal Infection

This study aims to estimate the pharmacokinetics (PK) of posaconazole (POS, MK-5592) intravenous (IV) and powder for oral suspension (PFS) formulations in pedi…

Invasive Fungal Infection

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT04665037

Phase 2

Randomized Clinical Trial to Evaluate the Use of Genotype-based Dosing of Voriconazole

This project aims to address invasive fungal infections in patients, by precision dosing of voriconazole based on CYP2C19 genotype testing with Bayesian dose-f…

Fungal InfectionHaematological MalignancyBlood Cancer+1 more

Estimated

~$10 – $6,250

The University of QueenslandNCT06510699

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (…

Pulmonary Invasive Fungal InfectionsPulmonary Invasive Aspergillosis

Estimated

~$10 – $750

Arkansas Children's Hospital Research InstituteNCT03827694