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3 recruiting studies matching your filters
Phase 2
A Phase 2, Open-label, Multicenter Study to Evaluate Efficacy and Safety of Zanidatamab for the Treatment of Participants With Previously Treated HER2-expressing Solid Tumors (DiscovHER PAN-206)
The purpose of this study is to evaluate the efficacy and safety of zanidatamab for the treatment of participants with previously treated solid tumors that hav…
Breast CancerGastric CancerEsophageal Cancer+9 more
Jazz PharmaceuticalsNCT06695845
Phase 1
PRE-Investigation of Serial Studies to Predict Your Therapeutic Response With Imaging And moLecular Analysis: A Phase I/Ib Platform Trial
I-SPY Phase I/Ib (I-SPY-P1) is an open-label, multisite platform study designed to evaluate single agents or combinations in a metastatic treatment setting tha…
HER2-positive Breast CancerMetastatic CancerMetastatic Breast Cancer+18 more
QuantumLeap Healthcare CollaborativeNCT05868226
Phase 1
Phase I Study of HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma (HEROS 3.0)
The purpose of this study is to learn whether it is safe to give HER2-CAR T cells in combination with an immune checkpoint inhibitor drug (pembrolizumab or niv…
SarcomaHER-2 Protein OverexpressionOsteosarcoma+5 more
Baylor College of MedicineNCT04995003