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An Experiment Evaluating the Effectiveness of Counter-marketing Food Messages Among Young Adults
The primary objective of this study is to identify the food counter-marketing messages (i.e., messages that describe deceptive marketing tactics used by food c…
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy
Title: Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy People for the Expansion of T Cells for Adoptive Cell Therapy Background: New th…
Evaluation of [11C]ZTP-1 to Image PDE4B
Background: PDE4B is a protein in cells that helps turn off certain chemical signals after they ve done their job. It controls inflammation, immune responses,…
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Background: Most medications that treat depression take weeks or months to work. Researchers want to develop fast-acting treatments. One dose of ketamine has …
Digital Measures for Clinical Trial Endpoints in Huntington's Disease (MEND-HD)
MEND-HD is a longitudinal study evaluating the feasibility of passive monitoring of gait and chorea in patients with HD and the meaningfulness of these outcome…
Patient Navigators for Children's Community Mental Health Services in High Poverty Urban Communities
The purpose is to study a model of mental health navigation for African American and Latinx children (0-14 years) in high poverty urban communities focused on …
A Phase 1/2a, First-in-human, Randomized, Double-blinded, Placebo-controlled, Dose-finding Study in Healthy Volunteers and Participants With Sickle Cell Disease to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics, pH and Food Effect, and Preliminary Efficacy of BMS-986470
The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BM…
Cytapheresis of Volunteer Donors
Background: \- National Institute on Aging researchers are looking at studies that require large numbers of white blood cells for lab use. Standard blood samp…
The Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults >= 55 Years Old. A Randomized Triple-Masked Controlled Clinical Trial
Background: As people age, the cells in the pancreas that produce insulin begin to release less of this hormone, and levels of blood glucose (sugar) rise. Thi…
The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Background: \- Biomarkers are substances in people's blood and tissues. They help researchers understand diseases and signs of aging. Scientists want to do mo…
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism: A Natural History Study
Background: Many people in the United States are overweight or obese. This natural history study will look into how life events during childhood can impact ea…
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle
Background: \- Magnetic resonance imaging (MRI) is a widely used scanning technique to obtain images of the human body and evaluate activity in the brain. A p…