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Single-tracer Multiparametric PET Imaging
The overarching goal of this project is to develop and evaluate a single-tracer multiparametric positron emission tomography (PET) imaging solution for simulta…
Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures
This is an unblinded pilot study of an environmental exposure to secondhand cannabis smoke in one group of healthy nonsmokers.
Combined Cardiac Rehabilitation and Inspiratory Muscle Training in Heart Failure
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure respo…
Supraspinatus Tendon Acute Effects After Two Exercise Exposures: a Crossover Randomized Trial.
The purpose of this study is to understand acute tendon changes after two exercise programs. We will invite individuals with and without shoulder pain to parti…
A Phase 1, Randomized, Investigator- and Participant-Blinded, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Characterize the Safety, Tolerability, and Pharmacokinetics of LY4515100 in Healthy Participants
The main purpose of this study is to assess the safety and tolerability of LY4515100 when given orally to healthy participants. Blood tests will be performed t…
Cardiomyocyte Specific Cell Free DNA as a Marker of Cardiac Sarcoidosis
Sarcoidosis is a multisystem granulomatous disease of unknown cause that can affect any organ in the body, including the heart. Granulomatous myocarditis can l…
Prevalence Effects in Visual Search: Theoretical and Practical Implications (J)
The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tas…
iSpecimen Network Protocol: Collection and Distribution of Remnant and Research Use Only Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capa…
Evaluating the Physiological and Psychological Impact of Low-Frequency Vibration Therapy: A Longitudinal Randomized Clinical Trial
The goal of this randomized clinical trial is to learn whether a low-frequency "kinetic wellness" mat (a comfortable mat that gently vibrates) can improve stre…
Restrict and Strengthen: Unraveling the Impact of Blood Flow Restriction Training on Upper Extremity Grip Strength
The primary objective of this prospective study is to investigate the effects of Blood Flow Restriction (BFR) training compared to traditional low-weight resis…
A Phase 1, Open Label, Randomized, Multiple Ascending Dose (MAD) Study Evaluating the Safety, Tolerability and Pharmacokinetics of KSHN001034 in Healthy Postmenopausal Female Volunteers
The goal of this clinical trial is to evaluate if KSHN001034 demonstrates safety, tolerability, and a comparable pharmacokinetic (PK) profile to the reference …
A Phase 1, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Safety and Pharmacokinetics of Bemnifosbuvir and Ruzasvir Administered as a Fixed-Dose Combination in Adult Participants With Severe Renal or Hepatic Impairment in Comparison to Healthy Participants
To Assess the Effect of Severe Hepatic or Renal Impairment on the Pharmacokinetics of Bemnifosbuvir/Ruzasvir After a Single Dose