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Measure Striatal Adenosine-dopamine Receptors Interactions: from Molecule to Behaviors
This research study aims to determine whether and how caffeine intake affects learning process through reward feedback compared to placebo. The data acquired f…
Disrupted Sleep in Somali Americans - Implications for Hypertension Risk
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a rese…
Understanding the Acute Modulation of Brain Activity by Transcranial Magnetic Stimulation
Background: Transcranial magnetic stimulation (TMS) is form of non-invasive brain stimulation. It is approved to treat depression. TMS may help decrease drug …
Pilot Study to Evaluate Feasibility of Sensory Stimulation With Gamma Frequency Entrainment
Despite the huge healthcare and economic impact of AD, there is still no disease modifying therapeutics available. In fact, the available therapeutics show low…
Drug Discovery for Parkinson's With Mutations in the GBA Gene
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Parkinson's disease research and drug development by usi…
Intermountain Healthcare's - PRECISion MEdicine Biobank
The immediate goal of this study is to collect biological samples (i.e., tissue and/or fluid), clinical information, and laboratory data from disease and non-d…
Theta-burst Stimulation Modulates Criticality and Cognitive Control
The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults…
Assessing the Application of Closed Incision Negative Pressure Wound Therapy to Reduction Mammaplasty
In this prospective, randomized, split-body control trial, we aim to compare complications, patient-reported outcomes, and cost differentials following reducti…
Airway Data Collection With the Entarik Feeding Tube System
The purpose of this study is to evaluate the airway detection performance of the Entarik Feeding Tube System, and to collect data when the Entarik Feeding Tube…
EVax-3: Human Upper and Lower Airway Mucosal Immune Response to FluMist Vaccination
The goal of this clinical trial is to measure the immune response in the blood, nose, and lungs after participants receive either the FDA-approved inactivated …
Oral Microbial and Immunological Characterization of Patients With Immune Dysfunction
Background: \- Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This condition can cause tooth loss if it is…
A Phase 1, Open-Label, Two-Cohort Study to Assess the Effect of a Strong CYP3A4 Inducer on the Pharmacokinetics of Atumelnant and the Effect of Atumelnant on the Pharmacokinetics of CYP3A4, P-gp, and MATE1/2-K Substrates in Healthy Participants
This study aims to evaluate the impact of strong CYP3A4 induction on the pharmacokinetics (PK) of atumelnant, as well as the effect of atumelnant on CYP3A4, P-…