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748 recruiting studies matching your filters

The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

This study will test the effects of psilocybin on memory and cognition in healthy participants using computerized tasks and magnetic resonance imaging (MRI).

Healthy

Estimated

~$10 – $7,500

Manoj DossNCT07079852

Observational

The Impacts of Multivitamin and Mineral Supplementation on Cellular Metabolism and Healthy Aging

The goal of this study is to determine the impact of MVM supplementation on clinical and biochemical markers associated with healthy aging, with a particular f…

Healthy AgingMultivitamin and Mineral Supplementation

Estimated

~$10 – $6,250

University of California, San DiegoNCT07642869

Phase 1

A Phase 1, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Pharmacokinetics of Inhaled TRL1068 in Healthy Volunteers

This study in healthy volunteers will provide a basis for evaluation of inhaled TRL1068 as a first in human study, specifically, important safety, tolerability…

Healthy Volunteer

Estimated

~$10 – $8,750

Trellis Bioscience LLCNCT07644195

Phase 1

A Phase 1, Multi-center, Open-label, Single-dose Study to Assess the Pharmacokinetics and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Mild and Moderate Hepatic Impairment

The purpose of this study is to determine the pharmacokinetic and safety of BMS-986435 in participants with normal hepatic function and participants with diffe…

Healthy VolunteersHepatic Impairment

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07248839

Phase 3

A Phase 3, Randomized, Modified Double-blind, Active-controlled, Parallel-group, Lot-to-lot Consistency, 4-arm Study to Investigate the Safety and Immunogenicity of a 4-dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers

This is a phase 3 randomized, modified double-blind study whose purpose is to measure whether 3 lots of the investigational pneumococcal vaccine PCV21 can help…

Pneumococcal ImmunizationHealthy Volunteers

A First in Human, Single Ascending Dose Study of ABBV-1451 to Evaluate the Pharmacokinetics, Immunogenicity, Safety, and Tolerability in Healthy Subjects and in Japanese and Han Chinese Healthy Subjects

The objective of this study is to assess the pharmacokinetic (PK), immunogenicity, safety, and tolerability of ABBV-1451 after single ascending doses in health…

Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.

The primary objective of this study is to measure the concentration and the regional brain distribution of activated brain microglia/macrophages using the PET …

FibromyalgiaChronic Fatigue SyndromeMultiple Sclerosis+1 more

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT03759522

Phase 1

A Phase 1, Open-Label, Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Varegacestat Administered in Different Dose Forms in Healthy Participants

This is an open-label, randomized, crossover study to evaluate the relative bioavailability (rBA) and bioequivalence (BE) of a test capsule formulation of vare…

Healthy

Estimated

~$10 – $8,750

Immunome, Inc.NCT07610005

Observational

Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model

This study seeks to understand individual differences in personality, brain function, and behavior. Study hypothesis: \- A stronger sign-tracking bias will b…

Substance UseHealthy

Estimated

~$10 – $6,250

University of MichiganNCT07094061

Phase 1

An Adaptive Two-Stage Bioequivalence Study of Subcutaneous Injections of Mirikizumab Solution in Healthy Participants

The main purpose of this study is to assess the safety and tolerability of mirikizumab (LY3074828) solution formulation administered as a single injection comp…

Healthy

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07446101

Phase 1

A Phase I Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of AZD1613 Following Single and Multiple Dose Administration in Healthy Participants

The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of AZD1613 in healthy particip…

Healthy

Estimated

~$10 – $7,500

AstraZenecaNCT06995820

Phase 1

An Open-label Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults.

The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laropr…

Healthy Participants

Estimated

~$10 – $7,500

AstraZenecaNCT07513571