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66 recruiting studies matching your filters

An Open-label Study to Assess the Effect of AZD0780 on the Pharmacokinetics of AZD4954 and Vice Versa in Healthy Adults.

The purpose this study is to measure the impact of laroprovstat (AZD0780) on the pharmacokinetics (PK) of AZD4954 and the impact of AZD4954 on the PK of laropr…

Healthy Participants

Estimated

~$10 – $7,500

AstraZenecaNCT07513571

Observational

Multi-Channel Spinal Transcutaneous Electrical Pulsed Stimulation System: STEPSS

The purpose of this study is to compare updated spinal stimulation devices with the spinal stimulation device that is currently used. Spinal stimulation is oft…

Healthy Participants

Estimated

~$10 – $7,500

Gail ForrestNCT07217314

Phase 1

An Open-Label, Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants

The purpose of this study is to evaluate the interstitial concentrations using the open-flow microperfusion device and plasma pharmacokinetics following multip…

Healthy Participants

Estimated

~$10 – $8,750

Incyte CorporationNCT07588139

Phase 2

2 x 2 Factorial, Double-blind, Randomized Trial of 'Set and Setting': a Translational Study in Healthy Volunteers

One hundred twenty healthy participants, ages 21 to 70, who experience moderate-to-lower-than-average mental well-being will be evenly randomized into four dif…

Healthy Participants With Lower-than-average Mental Well-being

Estimated

~$10 – $7,500

Robin Carhart-Harris, PhD, MANCT06626139

Phase 3

Cognitive Strategies in Early Psychosis 1

The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do …

CognitionHealthy Participants

Estimated

~$10 – $6,250

University of MinnesotaNCT07231497

Observational

A Randomized, Double-Blind, Placebo-Controlled Decentralized Trial to Assess the Effect and Tolerability of Limosilactobacillus Reuteri DSM 17648 Supplement in Healthy Adults Reporting Upper Gastrointestinal Discomfort

The goal of this clinical trial is to learn if the food supplement containing a postbiotic (inanimate) Limosilactobacillus reuteri DSM 17648 works to improve t…

Healthy ParticipantsUpper Gastrointestinal Discomfort

Estimated

~$10 – $7,500

Novozymes A/SNCT07163637

Phase 1

Researching Economical Adjuvants to Cancer Therapy

The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the invest…

Healthy Participants

Estimated

~$10 – $6,250

Florida State UniversityNCT07305259

Observational

Effects of Pistachio Snacking on Metabolic Flexibility in Healthy Overweight and Obese Adults

The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) i…

Overweight (BMI > 25)Obese But Otherwise Healthy ParticipantsOverweight or Obese+4 more

Estimated

~$10 – $6,250

University of South CarolinaNCT07340125

Phase 1

A First in Human, Phase 1/1b Study of Single and Multiple Ascending Dosing Administration of NTX110253 in Healthy Participants and Participants With Stable Schizophrenia

This study will assess the safety, tolerability, and pharmacokinetics of NTX-253 following oral administration in both healthy adult participants as well as ad…

Healthy ParticipantsSchizophrenia Diagnosis

Estimated

~$10 – $7,500

NeurosterixNCT07344948

Phase 1

A Randomized, Phase 1, Open-Label, Two-Treatment, Two- Period, Two-Sequence, Single-Dose Crossover Study to Evaluate the Effect of Food on the Relative Bioavailability of Nalbuphine Extended-Release Tablets (NAL ER) in Healthy Subjects

The primary purpose of this study is to evaluate the effect of a high-fat, high-calorie meal on the relative bioavailability of NAL ER following single oral do…

Healthy Participants

Estimated

~$10 – $8,750

Trevi TherapeuticsNCT07487740

Phase 1

A PHASE 1, NON-RANDOMIZED, OPEN-LABEL, SINGLE-DOSE, PARALLEL GROUP STUDY TO COMPARE THE PHARMACOKINETICS OF VEPDEGESTRANT (PF-07850327) IN ADULT PARTICIPANTS WITH MODERATE AND SEVERE HEPATIC IMPAIRMENT RELATIVE TO HEALTHY PARTICIPANTS WITH NORMAL HEPATIC FUNCTION

The purpose of the study is to look at how the body processes a study medicine called vepdegestrant in participants with loss of liver function relative to peo…

First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands ([18F]ABBV964i and [ 18F]ABBV-965i) as Potential PET Radioligands for Imaging Tau Protein in the Brain of Patients With Probable PSP and Healthy Volunteers

This clinical study is being conducted to learn more about two new imaging drugs, called \[18F\]ABBV-964i and \[18F\]ABBV-965i, which are designed to help doct…

Progressive Supranuclear Palsy (PSP)Healthy Participants

Estimated

~$10 – $7,500

InvicroNCT07348276